Rabbit Anti-a2M Antibody (MOFY-0622-FY197)
Cat: MOFY-0622-FY197
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Rabbit |
| Species Reactivity | Rabbit |
| Immunogen | Recombinant Alpha-2-Macroglobulin (a2M) |
| Format | Liquid or Lyophilized |
| Buffer | 0.01M PBS, pH7.4, 50% glycerol |
| Regulatory Status | For Research Use Only. Not For Clinical Use. |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Application Information
| Application | WB, IHC, ICC, IP |
| Application Notes | WB: 0.5-2 µg/mL IHC: 5-20 µg/mL ICC: 5-20 µg/mL The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016] |
| Alternative Names | A2MG; A2mg; CPAMD5; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 |
See other products for " A2M "
| MO-AB-50149W | Mouse Anti-Marmoset A2M Antibody (MO-AB-50149W) |
| CBMOAB-34738FYA | Mouse Anti-Rhesus A2M Antibody (CBMOAB-34738FYA) |
| MO-AB-17838W | Mouse Anti-Chimpanzee A2M Antibody (MO-AB-17838W) |
| MO-AB-06722R | Mouse Anti-Cattle A2M Antibody (MO-AB-06722R) |
| MO-AB-01108H | Mouse Anti-Frog a2m Antibody (MO-AB-01108H) |
| MO-AB-23433R | Mouse Anti-Pig A2M Antibody (MO-AB-23433R) |
For Research Use Only | Not For Clinical Use.
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