Mouse Anti-ACE Antibody (MOFAB-095W)


Cat: MOFAB-095W
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Specifications

Host speciesMouse
Species ReactivityHuman, Mouse, Bovine
SpecificityThe antibody specifically reacts with human, bovine and murine ACE and ACE-positive endothelial cells.
ImmunogenAngiotensin-converting enzyme purified from rat lung.
FormatLiquid or Lyophilized
BufferPBS, pH 7.4
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationPurified by precipitation with 6% polyethylene glycol (PEG)

Application Information

ApplicationELISA, IHC, FC
Application NotesThe optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.
Product OverviewThe ACE antibody is used as Enzymes and Enzyme Inhibitor Antibodies.
Alternative NamesAngiotensin I Converting Enzyme; Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1; Dipeptidyl Carboxypeptidase I; CD143 Antigen; Kininase II; DCP1; DCP; Angiotensin Converting Enzyme, Somatic Isoform; Angiotensin-Converting Enzyme; Angiotensin Converting Enzyme (ACE)
Gene ID1636
UniProt IDP12821
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For Research Use Only | Not For Clinical Use.
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