Mouse Anti-ACVR2B Antibody (CBMOAB-35057FYA)


Cat: CBMOAB-35057FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-35057FYA Monoclonal Rhesus (Macaca mulatta), Cattle (Bos taurus), Chicken (Gallus gallus), Frog (Xenopus laevis), Goat (Capra hircus), Pig (Sus scrofa), Sheep (Ovis aries), Zebrafish (Danio rerio) WB, ELISA MO35057FYA 100 µg
CBMOAB-64833FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO64833FYA 100 µg
MO-AB-00039Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO00039Y 100 µg
MO-AB-01220H Monoclonal Frog (Xenopus laevis) WB, ELISA MO01220C 100 µg
MO-AB-06976R Monoclonal Cattle (Bos taurus) WB, ELISA MO06976R 100 µg
MO-AB-14083Y Monoclonal Sheep (Ovis aries) WB, ELISA MO14083Y 100 µg
MO-AB-23519R Monoclonal Pig (Sus scrofa) WB, ELISA MO23519R 100 µg
MO-AB-36667W Monoclonal Goat (Capra hircus) WB, ELISA MO36667W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cattle (Bos taurus), Chicken (Gallus gallus), Frog (Xenopus laevis), Goat (Capra hircus), Pig (Sus scrofa), Sheep (Ovis aries), Zebrafish (Danio rerio)
CloneMO35057FYA
SpecificityThis antibody binds to Rhesus ACVR2B.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionActivins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Product OverviewMouse Anti-Rhesus ACVR2B Antibody is a mouse antibody against ACVR2B. It can be used for ACVR2B detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesActivin receptor type-2B; ACVR2B
UniProt IDH9Z1Q7
Protein RefseqThe length of the protein is 512 amino acids long.
The sequence is show below: MTAPWAALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI.
For Research Use Only | Not For Clinical Use.
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