Mouse Anti-Acy1 Antibody (CBMOAB-00919FYA)


Cat: CBMOAB-00919FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-00919FYA Monoclonal Fruit fly (Drosophila melanogaster), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Horse (Equus caballus), Marmoset, Nile tilapia (Oreochromis niloticus), Zebrafish (Danio rerio) WB, ELISA MO00919FYA 100 µg
CBMOAB-64840FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO64840FYA 100 µg
CBMOAB-00367HCB Monoclonal C. elegans (Caenorhabditis elegans) WB, ELISA MO00367HB 100 µg
MO-AB-25680W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO25680W 100 µg
MO-AB-28810W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO28810W 100 µg
MO-AB-43579W Monoclonal Horse (Equus caballus) WB, ELISA MO43579W 100 µg
MO-AB-50413W Monoclonal Marmoset WB, ELISA MO50413W 100 µg
MO-AB-06978R Monoclonal Cattle (Bos taurus) WB, ELISA MO06978R 100 µg
MO-AB-32805H Monoclonal Nile tilapia (Oreochromis niloticus) WB, ELISA MO32805C 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Horse (Equus caballus), Marmoset, Nile tilapia (Oreochromis niloticus), Zebrafish (Danio rerio)
CloneMO00919FYA
SpecificityThis antibody binds to fruit fly Acy1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.
Product OverviewMouse Anti-D. melanogaster Acy1 Antibody is a mouse antibody against Acy1. It can be used for Acy1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAminoacylase-1; EC 3.5.1.14; N-acyl-L-amino-acid amidohydrolase
UniProt IDQ8MRB5
Protein RefseqThe length of the protein is 401 amino acids long.
The sequence is show below: MSAEKWEKNEEIRIFREYLRIPSVHPNIDYTACVEFIKRQADSLNLPVEVVFPAVKSKPVVIIKWEGSQPKLPSIILSSHMDVVPVFPEMWTHEPFSADIDEEGRIFARGAQDMKSVGTQYLGVIRLLRADGFQPKRTLYVTFVPDEEIGGIHGMAAFVETDFYKQMNVGFSLDEGGTSASDVHHLFYAERIRWILKLKVAGTAGHGSLLLPDTAGVKLNYVLNKLTEFRESQIQRLKNDKSLSIGDVTTVNLTQLSGGVQSNVVPPLFEAIFDIRLAITLDLVAFEREIRNWCEEAGGGIDIEFPLKEAYVAATRLDDSNPYWLALKVALDELGLKVKPIVCFAVTDCRFIRQQGTPAIGFSPIINTTVLIHDHDEFLRADDYLNGIQVYKKIIPNLTEV.
For Research Use Only | Not For Clinical Use.
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