Mouse Anti-Arabidopsis ATG4B Antibody (CBMOAB-24518FYC)


Cat: CBMOAB-24518FYC
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
CloneMO24518FC
SpecificityThis antibody binds to Arabidopsis ATG4B.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Product OverviewMouse Anti-Arabidopsis ATG4B Antibody is a mouse antibody against ATG4B. It can be used for ATG4B detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAutophagy Related 4B Cysteine Peptidase; Autophagy-Related Cysteine Endopeptidase 1; Autophagy-Related Protein 4 Homolog B; AUT-Like 1 Cysteine Endopeptidase; Autophagin-1; HAPG4B; APG4B; AUTL1; ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae)
UniProt IDQ9M1Y0
Protein RefseqThe length of the protein is 477 amino acids long. The sequence is show below: MKAICDRFVPSKCSSSSTSEKRDISSPTSLVSDSASSDNKSNLTLCSDVVASSSPVSQLCREASTSGHNPVCTTHSSWTVILKTASMASGAIRRFQDRVLGPSRTGISSSTSEIWLLGVCYKISEGESSEEADAGRVLAAFRQDFSSLILMTYRRGFEPIGDTTYTSDVNWGCMLRSGQMLFAQALLFQRLGRSWRKKDSEPADEKYLEILELFGDTEASAFSIHNLILAGESYGLAAGSWVGPYAVCRSWESLARKNKEETDDKHKSFSMAVHIVSGSEDGERGGAPILCIEDVTKTCLEFSEGETEWPPILLLVPLVLGLDRVNPRYIPSLIATFTFPQSLGILGGKPGASTYIVGVQEDKGFYLDPHDVQQVVTVKKENQDVDTSSYHCNTLRYVPLESLDPSLALGFYCQHKDDFDDFCIRATKLAGDSNGAPLFTVTQSHRRNDCGIAETSSSTETSTEISGEEHEDDWQLL.

Reference

Reference1. Lal, N. K., Thanasuwat, B., Huang, P. J., Cavanaugh, K. A., Carter, A., Michelmore, R. W., & Dinesh-Kumar, S. P. (2020). Phytopathogen effectors use multiple mechanisms to manipulate plant autophagy. Cell host & microbe, 28(4), 558-571.
2. Yamada, T., Ichimura, K., Kanekatsu, M., & van Doorn, W. G. (2009). Homologs of genes associated with programmed cell death in animal cells are differentially expressed during senescence of Ipomoea nil petals. Plant and Cell Physiology, 50(3), 610-625.
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For Research Use Only | Not For Clinical Use.
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