Mouse Anti-Arabidopsis BARD1 Antibody (CBMOAB-25066FYC)
Cat: CBMOAB-25066FYC
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | A. thaliana (Arabidopsis thaliana) |
| Clone | MO25066FC |
| Specificity | This antibody binds to Arabidopsis BARD1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Plasma Membrane |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Product Overview | Mouse Anti-Arabidopsis BARD1 Antibody is a mouse antibody against BARD1. It can be used for BARD1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | BRCA1 Associated RING Domain 1; RING-Type E3 Ubiquitin Transferase BARD1; EC 2.3.2.27; BARD-1 |
| UniProt ID | F4I443 |
| Protein Refseq | The length of the protein is 714 amino acids long. The sequence is show below: MAEFTNMLMNPWVLHLQKLELELKCPLCLKLLNRPVLLPCDHVFCDSCVHKSSQVESGCPVCKSKHPKKARRDLRFMESVISIYKSLNAAVSVHLPQLQIPNDCNYKNDALNNSNSPKHGESEDSEMTDKDVSKRSGGTDSSSRDGSPLPTSEESDPRPKHQDWTEKQLSDHLLLYEFESEYDAANHTPESYTEQAAKNVRDITASEQPSNAARKRICGDSFIQESSPNPKTQDPTLLRLMESLRSDDPTDYVKAQNHQQLPKSHTEQDSKRKRDITASDAMENHLKVPKRENNLMQKSADIDCNGKCSANSDDQLSEKISKALEQTSSNITICGFCQSARVSEATGEMLHYSRGRPVDGDDIFRSNVIHVHSACIEWAPQVYYEGDTVKNLKAELARGMKIKCTKCSLKGAALGCFVKSCRRSYHVPCAREISRCRWDYEDFLLLCPAHSSVKFPNEKSGHRVSRAEPLPKINPAELCSLEQTPAFTKELVLCGSALSKSDKKLMESLAVRFNATISRYWNPSVTHVIASTDEKGACTRTLKVLMGILNGKWIINAAWMKASLKASQPVDEEPFEIQIDTQGCQDGPKTARLRAETNKPKLFEGLKFYFFGDFYKGYKEDLQNLVKVAGGTILNTEDELGAESSNNVNDQRSSSIVVYNIDPPHGCALGEEVTIIWQRANDAEALASQTGSRLVGHTWVLESIAGYKLHPVIG. |
See other products for " bard1 "
| MO-AB-01803H | Mouse Anti-Frog bard1 Antibody (MO-AB-01803H) |
| MO-AB-07968R | Mouse Anti-Cattle BARD1 Antibody (MO-AB-07968R) |
| MO-AB-21326W | Mouse Anti-Chimpanzee BARD1 Antibody (MO-AB-21326W) |
| CBMOAB-67436FYA | Mouse Anti-Zebrafish bard1 Antibody (CBMOAB-67436FYA) |
| CBMOAB-36774FYA | Mouse Anti-Rhesus BARD1 Antibody (CBMOAB-36774FYA) |
| MO-DKB-02312W | Rabbit Anti-BARD1 Antibody (MO-DKB-02312W) |
For Research Use Only | Not For Clinical Use.
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