Mouse Anti-Arabidopsis DUT Antibody (CBMOAB-27933FYC)
Cat: CBMOAB-27933FYC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Size: | |
Conjugate: | |
Inquiry |
- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | A. thaliana (Arabidopsis thaliana) |
Clone | MO27933FC |
Specificity | This antibody binds to Arabidopsis DUT. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Cytosol |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19. |
Product Overview | Mouse Anti-Arabidopsis DUT Antibody is a mouse antibody against DUT. It can be used for DUT detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Deoxyuridine Triphosphatase; DUTP Pyrophosphatase; DUTP Diphosphatase; EC 3.6.1.23; DUTPase; Deoxyuridine 5-Triphosphate Nucleotidohydrolase, Mitochondrial; DUTP Nucleotidohydrolase |
UniProt ID | Q9STG6 |
Protein Refseq | The length of the protein is 166 amino acids long. The sequence is show below: MACVNEPSPKLQKLDRNGIHGDSSPSPFFKVKKLSEKAVIPTRGSPLSAGYDLSSAVDSKVPARGKALIPTDLSIAVPEGTYARIAPRSGLAWKHSIDVGAGVIDADYRGPVGVILFNHSDADFEVKFGDRIAQLIIEKIVTPDVVEVDDLDETVRGDGGFGSTGV. |
See other products for " dut "
CBMOAB-0629YC | Mouse Anti-E. coli dut Antibody (CBMOAB-0629YC) |
CBMOAB-22552FYB | Mouse Anti-Rice DUT Antibody (CBMOAB-22552FYB) |
MO-AB-01959W | Mouse Anti-Rhesus DUT Antibody (MO-AB-01959W) |
MO-AB-25528W | Mouse Anti-Chimpanzee DUT Antibody (MO-AB-25528W) |
MO-AB-54601W | Mouse Anti-Marmoset DUT Antibody (MO-AB-54601W) |
MO-AB-11751R | Mouse Anti-Cattle DUT Antibody (MO-AB-11751R) |
MO-AB-03132H | Mouse Anti-Frog dut Antibody (MO-AB-03132H) |
CBMOAB-74250FYA | Mouse Anti-Zebrafish dut Antibody (CBMOAB-74250FYA) |
MO-AB-25515H | Mouse Anti-Rat Dut Antibody (MO-AB-25515H) |
For Research Use Only | Not For Clinical Use.
Online Inquiry