Mouse Anti-Arabidopsis GEN1 Antibody (CBMOAB-33945FYC)


Cat: CBMOAB-33945FYC
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
CloneMO33945FC
SpecificityThis antibody binds to Arabidopsis GEN1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.
Product OverviewMouse Anti-Arabidopsis GEN1 Antibody is a mouse antibody against GEN1. It can be used for GEN1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGEN1, Holliday Junction 5' Flap Endonuclease; GEN1, Holliday Junction 5 Flap Endonuclease; Holliday Junction Resolvase; Gen Endonuclease Homolog 1 (Drosophila); Flap Endonuclease GEN Homolog 1; Gen Endonuclease Homolog 1; EC 3.1.-.-; Gen
UniProt IDQ9LPD2
Protein RefseqThe length of the protein is 599 amino acids long. The sequence is show below: MGVGGNFWDLLRPYAQQQGFDFLRNKRVAVDLSFWIVQHETAVKGFVLKPHLRLTFFRTINLFSKFGAYPVFVVDGTPSPLKSQARISRFFRSSGIDTCNLPVIKDGVSVERNKLFSEWVRECVELLELLGIPVLKANGEAEALCAQLNSQGFVDACITPDSDAFLFGAMCVIKDIKPNSREPFECYHMSHIESGLGLKRKHLIAISLLVGNDYDSGGVLGIGVDKALRIVREFSEDQVLERLQDIGNGLQPAVPGGIKSGDDGEEFRSEMKKRSPHCSRCGHLGSKRTHFKSSCEHCGCDSGCIKKPLGFRCECSFCSKDRDLREQKKTNDWWIKVCDKIALAPEFPNRKIIELYLSDGLMTGDGSSMSWGTPDTGMLVDLMVFKLHWDPSYVRKMLLPMLSTIYLREKARNNTGYALLCDQYEFHSIKCIKTRYGHQSFVIRWRKPKSTSGYSHSHSEPEESIVVLEEEEESVDPLDGLNEPQVQNDNGDCFLLTDECIGLVQSAFPDETEHFLHEKKLRESKKKNVSEEETATPRATTMGVQRSITDFYRSAKKAAAGQSIETGGSSKASAEKKRQATSTSSSNLTKSVRRRLLFG.
For Research Use Only | Not For Clinical Use.
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