Mouse Anti-Arabidopsis MCM4 Antibody (CBMOAB-36306FYC)


Cat: CBMOAB-36306FYC
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
CloneMO36306FC
SpecificityThis antibody binds to Arabidopsis MCM4.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Nucleus; Cytosol; Chloroplast

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
Product OverviewMouse Anti-Arabidopsis MCM4 Antibody is a mouse antibody against MCM4. It can be used for MCM4 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMinichromosome Maintenance Complex Component 4; CDC21 Homolog; P1-CDC21; CDC21; MCM4 Minichromosome Maintenance Deficient 4 (S. Cerevisiae); Homolog Of S. Pombe Cell Devision Cycle 21; Minichromosome Maintenance Deficient 4
UniProt IDQ0WVF5
Protein RefseqThe length of the protein is 847 amino acids long. The sequence is show below: MASDSSLGNTNDGPPSPGENVSSPIENTYSSPAALHRRRRGRSSTPTQFATPPPPPSRLASSNSTPPTSRPSAARSKGRNGHGGGGGGGGGGDPGTPMSTDEPLPSSDDGEEDGGDDTTPTFVWGTNISVQDVKSAIEMFVKHFREARENSDDLFREGKYMVSIRKVIEIEGEWIDVDAFDVFDYDPDLYNKMVRYPLEVLAIFDIVLMDIVSTINRLFEKHVQVRIFNLRTSTSMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGYFSDPIIVDRGKISEPPTCLKQECMTKNSMTLVHNRCRFADKQIVRLQETPDEIPEGGTPHTVSLLLHDKLVDNGKPGDRIEVTGIYRAMTVRVGPAHRTVKSVFKTYIDCLHIKKASKLRMSAEDPMDVDNSLRRVDEDVELDEEKLRKFQELSKQPDIYERLSRSLAPNIWELDDVKKGLLCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHFENAESAQEEAIDITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAGKFAGSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVAMQQSATDHATGTIDMDLINTGVSASERMRRDTFASSIRDIALEKMQIGGSSMRLSELLEELKKHGGNINTEIHLHDVRKAVATLASEGFLVAEGDRIKRV.
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For Research Use Only | Not For Clinical Use.
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