Rabbit Anti-ArfA Antibody (MO-DKB-02348W)
Cat: MO-DKB-02348W
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- Product Details
Specifications
Host species | Rabbit (Oryctolagus cuniculus) |
Species Reactivity | A. thaliana (Arabidopsis thaliana) |
Immunogen | Synthetic peptides from Arabidopsis AT1G23490, AT5G14670, AT2G47170, AT1G70490, AT3G62290, AT301G, ArfAlA, ArfAlB, ArfAlC, ArfAlD, ArfAlE, ArfAlF. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | Peptide affinity purified |
Application Information
Application | WB |
Application Notes | Western Blot (1:1000-1:2000) Note: Optimal dilutions/concentrations should be determined by the end user. |
Target
Introduction | Rescues ribosomes stalled at the 3' end of non-stop mRNAs (PubMed:21062370, PubMed:21435036). This activity is crucial when the stalled ribosome cannot be rescued by the SsrA(tmRNA)-SmpB quality control system (PubMed:21062370, PubMed:21435036). Binds the 30S subunit, contacting 16S rRNA with the N-terminus near the decoding center and its C-terminus in the mRNA entry channel; contacts change in the presence of release factor 2 (RF2, also named PrfB) (PubMed:25355516, PubMed:27906160, PubMed:27906161, PubMed:27934701, PubMed:28077875). Requires RF2/PrfB to hydrolyze stalled peptidyl-tRNA on the ribosome; recruits and probably helps position RF2/PrfB correctly in the ribosomal A site so RF2's GGQ motif can hydrolyze the peptidyl-tRNA bond (PubMed:22857598, PubMed:22922063, PubMed:25355516, PubMed:27906160, PubMed:27906161, PubMed:27934701, PubMed:28077875). Does not release ribosomes with a programmed pause caused by regulatory chains such as SecM-mediated pausing (PubMed:22857598). Binds tRNA which may stimulate its ribosome rescue activity (PubMed:22857598). |
Product Overview | This product is a Rabbit antibody against the ArfA. It can be used for ArfA detection in Western Blot. |
Alternative Names | Alternative ribosome-rescue factor A; arfA; yhdL; b4550 JW3253; ArfA |
See other products for " arfA "
CBMOAB-0136YC | Mouse Anti-E. coli arfA Antibody (CBMOAB-0136YC) |
For Research Use Only | Not For Clinical Use.
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