Mouse Anti-ASD2 Antibody (CBMOAB-00680HCB)

Cat: CBMOAB-00680HCB

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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-00680HCB	Monoclonal	C. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana)	WB, ELISA	MO00680HB		100 µg	Inquiry
Protein Refseq: The length of the protein is 486 amino acids long. The sequence is show below: MLSTMVHHFDANDYVSADWKPEPTLTTTATTDPLVATSSSSTTSSESHVTTASTSAPQSPTLLAPPISLQDVMTHASTDLLTPNGSANGVSTSQQQQYSAEYLSQLLKDKKQLAAFPNVFHHLERLADEEINKVRVVLFQCEFSKESAPLPDAEGDSTVHTEKVFVPAKEHPDYNFVGRILGPRGMTAKQLEQETGCKIMVRGRGSMRDKKKEELNRGKPNWEHLSEELHVLIQCEDTENRAKVKLMRAVEEVRKLLVPAPEGEDDLKRKQLMELAIINGTYRSGTDQSALAAAQLAAVKHQQQPFAAALQAAALQRGVLPMMANGLSRSPTMAVCGAPIVMSPSGRASSAGATATSQAALIMQQQSQLHAANAGNAALQQQAALLQQQQAAEYQQLLLSQAGLYDFSAMQQQYAAVGQNAAVAAAQAQAQAQYGALAAAAAANSAGNQQYADYAGVDLTSQQSAHGAMLNNRRLLGASREHPYKQ.
CBMOAB-2728FYC	Monoclonal	A. thaliana (Arabidopsis thaliana)	WB, ELISA	MO2728FC		100 µg	Inquiry
Protein Refseq: The length of the protein is 674 amino acids long. The sequence is show below: MDMETSWRFLRSVCLLSFILGSFSVYQTLCLVDAQEDAIVTLQVDASNVTRRPIPETLFGIFFEEINHAGAGGLWAELVSNRGFEAGGQIIPSNIWPWSIIGDESSIYVVTDRSSCFERNKIALRMEVLCDSNSCPLGGVGVYNPGYWGMNIEEGKKYKVVLYVRSTGDIDVSVSFTSSNGSVTLASENIIALASDLLNWTKKEMLLEANGTDNGARLQFTTTKKGSIWFDQVSAMPMDTYKGHGFRNDLFQMMVDLKPRFIRFPGGCFVEGDWLGNAFRWKETVRAWEERPGHYGDVWKYWTDDGLGHFEFFQLAEDLGASPIWVFNNGISHNDQVETKNVMPFVQEAIDGIEFARGDSNSTWGSVRAAMGHPEPFELKYVAVGNEDCFKSYYRGNYLEFYNAIKKAYPDIKIISNCDASAKPLDHPADYFDYHIYTLARDLFSKSHDFDNTPRNGPKAFVSEYAVNKADAKNGNLLAALGEAAFLLGLEKNSDIVEMVSYAPLFVNTNDRRWIPDAIVFNSSHLYGTPSYWVQHFFTESSGATLLNSTLKGKTSSVEASAISFQTNGKDYIQIKAVNFGEQSVNLKVAVTGLMAKFYGSKKKVLTSASVMDENSFSNPNMIVPQESLLEMTEQEDLMFVLPPHSFSSFDLLTESENVIKMPISDSYKKTSTM.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	C. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana)
Clone	MO00680HB
Specificity	This antibody binds to C. elegans ASD2.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Nucleus; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	RNA-binding protein that binds to the 5''-NACUAAY-N(1,20)-UAAY-3'' consensus sequence in pre-mRNA introns to promote alternative splicing (PubMed:18230701, PubMed:20573244, PubMed:23071450). Required for mutually exclusive alternative splicing where it modulates the switch between mutually exclusive exons during pre-mRNA maturation (PubMed:18230701, PubMed:23071450). Involved in muscle-specific gene expression regulating the alternative splicing of genes such as let-2 and unc-60 to ensure that their respective isoforms are expressed in muscle (PubMed:18230701, PubMed:23071450). Promotes the removal of intron 10 from let-2 pre-mRNA to allow for the exclusive expression of the muscle-specific let-2 isoform (as opposed to the non-muscle-specific isoform expressed in embryos) in body wall muscles during late larval and adult stages of development (PubMed:18230701). Binds cooperatively with RNA-binding protein sup-12 to intron 1A of the unc-60 pre-mRNA to promote alternative splicing and expression of the muscle specific isoform of unc-60 (PubMed:23071450).
Product Overview	Mouse Anti-C. elegans ASD2 Antibody is a mouse antibody against ASD2. It can be used for ASD2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	RNA-binding protein asd-2, isoform d; asd-2
Gene ID	188703
UniProt ID	D4YW53
Protein Refseq	The length of the protein is 486 amino acids long. The sequence is show below: MLSTMVHHFDANDYVSADWKPEPTLTTTATTDPLVATSSSSTTSSESHVTTASTSAPQSPTLLAPPISLQDVMTHASTDLLTPNGSANGVSTSQQQQYSAEYLSQLLKDKKQLAAFPNVFHHLERLADEEINKVRVVLFQCEFSKESAPLPDAEGDSTVHTEKVFVPAKEHPDYNFVGRILGPRGMTAKQLEQETGCKIMVRGRGSMRDKKKEELNRGKPNWEHLSEELHVLIQCEDTENRAKVKLMRAVEEVRKLLVPAPEGEDDLKRKQLMELAIINGTYRSGTDQSALAAAQLAAVKHQQQPFAAALQAAALQRGVLPMMANGLSRSPTMAVCGAPIVMSPSGRASSAGATATSQAALIMQQQSQLHAANAGNAALQQQAALLQQQQAAEYQQLLLSQAGLYDFSAMQQQYAAVGQNAAVAAAQAQAQAQYGALAAAAAANSAGNQQYADYAGVDLTSQQSAHGAMLNNRRLLGASREHPYKQ.

For Research Use Only | Not For Clinical Use.

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