Mouse Anti-ATOH8 Antibody (CBMOAB-36523FYA)

Cat: CBMOAB-36523FYA

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Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-36523FYA	Monoclonal	Rhesus (Macaca mulatta), Cat (Felis catus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Frog (Xenopus laevis), Horse (Equus caballus), Marmoset, Zebrafish (Danio rerio)	WB, ELISA	MO36523FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 263 amino acids long. The sequence is show below: ILLCAPPARPAPSEPPAPQAPPESTVRPAPPTRPGESSYSSISHVIYNNHPDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLDYSADHSNLSFSECVQRCTRTLQAEGRAKKRKSLIITQDTTARAAGLEAAGKTVQKVLCERGSSLMNNRTGRRKSWRLEFLFLRRRGFLLTFYLWFLFFSHFLLMLFLPLLTSVVTFFPPLRARRPPH.
CBMOAB-66971FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO66971FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 266 amino acids long. The sequence is show below: MKNPHLNSPCKILNTVSGDKKMKRKAREPIKHVSEDHYPYFKLYKNPHLMAETLGDGSPQETHRSEIITSRDDSVRNDVLNTAVDMRINTITAAEVPDSKLRSVSEKTVNSKIVQASPQVSVLSAPQVFPLERVVLSQRAASQAPAGGSERAESPRKRAGEPSGVVTEIKAIQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLAQLADLDYTPDHRNMSFRECVEQCTRTLQAEGRSKKRKE.
MO-AB-00212Y	Monoclonal	Chicken (Gallus gallus)	WB, ELISA	MO00212Y		100 µg	Inquiry
Protein Refseq: The length of the protein is 221 amino acids long. The sequence is show below: MRSTPLAEGEPWPRLCPAAELGGPRRLRRKHGCKSFRVELKVLSGRRPGLRAPPAPPPPPPAPPPAWEPRGAAALGAAAAASAFPAAPPPPPPPAAARPQPPPPPPAASPRPRPGEAAGVSPEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLGYSADHSNMSFSECVEQCTRTLQAEGRSKKRKE.
MO-AB-01691H	Monoclonal	Frog (Xenopus laevis)	WB, ELISA	MO01691C		100 µg	Inquiry
Protein Refseq: The length of the protein is 246 amino acids long. The sequence is show below: MKNLQLVEEKPWKSHCIKEIRRLKRKSREEAGIKPVNGMKSFKVDLKVDEAPAAAAAGERTGQLELLGGRAGEHVIEEEALDLRNNAVYLGKKGLMKSRGSEGQQQPRMVICPTRPPPETPYLPAPYSPDPSASPRKQPGETPGVTSEIKAIQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLDYSSDHSNLSFSECVEQCTRTLQSEGRSKKRKE.
MO-AB-08609W	Monoclonal	Cat (Felis catus)	WB, ELISA	MO08609W		100 µg	Inquiry
Protein Refseq: The length of the protein is 259 amino acids long. The sequence is show below: MKHIPVLEDGPWKTVCVKELNGLKKLKRKGKEPARRANGYKTFRLDLEAPEHGATATNGLRDRTQKLQPVAGPVPAPAAPAVPSGGGADPAGERRGARAPEVSDARKRGFALGAVGPGLPTPPPPPPPPPPPPPVPASQGQVPGGPEAQPFREPGLRPRILLCAPPARPTPSAPPAPPESSVRPAPPTRPGESSYSSISHVIYNNHPDSSASPRKRPGEATTAASEIKALQQTRRLLANARERTRVHTISAAFEALRKQ.
MO-AB-19128W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO19128W		100 µg	Inquiry
Protein Refseq: The length of the protein is 323 amino acids long. The sequence is show below: MKHIPVLEDGPWKTVCVKELNGLKKLKRKGKEPARRANGYKTFRLDLEAPEPRAVATNGLRDRTHRLQPVPVPVPVPVPVAPAVPPRGGTDTAGERGGSRAPEVSDARKRCFALGAVGPGLPTPPPPPPPPPPAPQSQATGGPEAQPFREPGLRPRILLCAPPARPAPSAPPAPPAPESTVRPAPPTRPGESSYSSISHVIYNNHPDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLDYSADHSNLSFSECVQRCTRTLQAEGRAKKRKE.
MO-AB-27111W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO27111W		100 µg	Inquiry
Protein Refseq: The length of the protein is 64 amino acids long. The sequence is show below: VPCYSYGQKLSKLAILRIACNYILSLARLADLDYSADHSNLSFSECVQRCTRTLQAEGRAKKRK.
MO-AB-29075W	Monoclonal	Dog (Canis lupus familiaris)	WB, ELISA	MO29075W		100 µg	Inquiry
Protein Refseq: The length of the protein is 152 amino acids long. The sequence is show below: MKHIPILEDGPWKTVCVKELNGLKKLKRKGKEPARRANGYKTFRLDLEAPERAAAAAAATNGLRDGTQRLQPVAAPVPAPAAPAVPSGGGADPAGERRGARAPEVPDARKRGFALGAAGPGLPTPPPPPPPPGQGPGGPGAQPFREPGLRPR.
MO-AB-43757W	Monoclonal	Horse (Equus caballus)	WB, ELISA	MO43757W		100 µg	Inquiry
Protein Refseq: The length of the protein is215 amino acids long. The sequence is show below: MKHIPVLEDGPWKTVCVKELNGLKKLKRKGKEPARRANGYKTFRLDLEAPEHGAAATNGLRDRTQRLQPVPAPVLAPVAPAVPSGGGADTAGERGGARAPEVLDARKRGFALGAVGPGLPTPPPLPPPPAPQGQVPGGPEAQPFREPGLRPRILLCAPPARPTPSAPPAPLESPARPAPLTRPGESSYSSISHVIYNNHPDSSASPRKRPGEATA.
MO-AB-51495W	Monoclonal	Marmoset	WB, ELISA	MO51495W		100 µg	Inquiry
Protein Refseq: The length of the protein is 324 amino acids long. The sequence is show below: MKHIPVLEDGPWKTVCVKELNGLKKLKRKGKEPARRANGYKTFRLDLEAPEPRAVATNGLRDRTHRLQPVPVPVPVPAPVAPAAPPRGGADTAGEHGGSRVPEVSDARKRGFALGAVGPGLPTTTTPPPPVPQSLAPGGAETQPFREPGLRPRILLCAPPARPKPSAPPAPPAPPAPPESTVRPPPPARPGESSYSSISHVIYNNHPDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLDYSADHSNLSFSECVQRCTRTLQAEGRAKKRKE.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Rhesus (Macaca mulatta), Cat (Felis catus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Frog (Xenopus laevis), Horse (Equus caballus), Marmoset, Zebrafish (Danio rerio)
Clone	MO36523FYA
Specificity	This antibody binds to Rhesus ATOH8.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5-CANNTG- 3 known as an E-box element, possibly as a heterodimer with other bHLH proteins (PubMed:24236640). Regulates endothelial cell proliferation, migration and tube-like structures formation (PubMed:24463812). Modulates endothelial cell differentiation through NOS3 (PubMed:24463812). May be implicated in specification and differentiation of neuronal cell lineages in the brain (By similarity). May participate in kidney development and may be involved in podocyte differentiation (By similarity). During early embryonic development is involved in tissue-specific differentiation processes that are dependent on class II bHLH factors and namely modulates the differentiation program initiated by the pro-endocrine factor NEUROG3 (By similarity). During myogenesis, may play a role during the transition of myoblasts from the proliferative phase to the differentiation phase (By similarity). Positively regulates HAMP transcription in two ways, firstly by acting directly on the HAMP promoter via E-boxes binding and indirectly through increased phosphorylation of SMAD protein complex (PubMed:24236640). Repress NEUROG3-dependent gene activation in a gene-specific manner through at least two mechanisms; requires only either the sequestering of a general partner such as TCF3 through heterodimerization, either also requires binding of the bHLH domain to DNA via a basic motif (By similarity).
Product Overview	Mouse Anti-Rhesus ATOH8 Antibody is a mouse antibody against ATOH8. It can be used for ATOH8 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	ATOH8
UniProt ID	F7CKC4
Protein Refseq	The length of the protein is 263 amino acids long. The sequence is show below: ILLCAPPARPAPSEPPAPQAPPESTVRPAPPTRPGESSYSSISHVIYNNHPDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLDYSADHSNLSFSECVQRCTRTLQAEGRAKKRKSLIITQDTTARAAGLEAAGKTVQKVLCERGSSLMNNRTGRRKSWRLEFLFLRRRGFLLTFYLWFLFFSHFLLMLFLPLLTSVVTFFPPLRARRPPH.

For Research Use Only | Not For Clinical Use.

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