Rabbit Anti-BAG3 Antibody (MO-DKB-00780W)
Cat: MO-DKB-00780W
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- Product Details
Specifications
Host species | Rabbit (Oryctolagus cuniculus) |
Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), Rhesus (Macaca mulatta) |
Immunogen | Recombinant protein containing sequences in the C-terminal region of human BAG3. |
Epitope | The epitope is in the C-terminal of BAG3. |
Format | Liquid or Lyophilized |
Buffer | PBS, pH 7, 10% Glycerol |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | Affinity purified |
Application Information
Application | WB, IB, IHC, IHC-P |
Application Notes | Western Blot 1:500-1:3000 Immunoblotting 1:100-1:2000 Immunohistochemistry 1:100-1:1000 Immunohistochemistry-Paraffin 1:100-1:1000 |
Target
Introduction | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008] |
Product Overview | This product is a Rabbit antibody against the C-terminal of the BAG3. It can be used for BAG3 detection in Western Blot, Immunoblotting, Immunohistochemistry, Immunohistochemistry-Paraffin. |
Alternative Names | BCL2 Associated Athanogene 3; Bcl-2-Binding Protein Bis; Docking Protein CAIR-1; BAG-3; BIS; BAG Family Molecular Chaperone Regulator 3; |
Gene ID | 9531 |
UniProt ID | O95817 |
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CBMOAB-25039FYC | Mouse Anti-Arabidopsis BAG3 Antibody (CBMOAB-25039FYC) |
MO-AB-23119W | Mouse Anti-Chimpanzee BAG3 Antibody (MO-AB-23119W) |
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For Research Use Only | Not For Clinical Use.
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