Rabbit Anti-BAG3 Antibody (MO-DKB-00780W)


Cat: MO-DKB-00780W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), Rhesus (Macaca mulatta)
ImmunogenRecombinant protein containing sequences in the C-terminal region of human BAG3.
EpitopeThe epitope is in the C-terminal of BAG3.
FormatLiquid or Lyophilized
BufferPBS, pH 7, 10% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified

Application Information

ApplicationWB, IB, IHC, IHC-P
Application NotesWestern Blot 1:500-1:3000
Immunoblotting 1:100-1:2000
Immunohistochemistry 1:100-1:1000
Immunohistochemistry-Paraffin 1:100-1:1000

Target

IntroductionBAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
Product OverviewThis product is a Rabbit antibody against the C-terminal of the BAG3. It can be used for BAG3 detection in Western Blot, Immunoblotting, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesBCL2 Associated Athanogene 3; Bcl-2-Binding Protein Bis; Docking Protein CAIR-1; BAG-3; BIS; BAG Family Molecular Chaperone Regulator 3;
Gene ID9531
UniProt IDO95817
For Research Use Only | Not For Clinical Use.
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