Rabbit Anti-BARD1 Antibody (MO-DKB-02312W)
Cat: MO-DKB-02312W
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | A. thaliana (Arabidopsis thaliana) |
| Immunogen | BARD1 synthetic peptide derived from Arabidopsis AT1G04020. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Peptide affinity purified |
Application Information
| Application | WB, Co-IP |
| Application Notes | Western Blot (1:1000-1:2000), Co-IPNote: Optimal dilutions/concentrations should be determined by the end user. |
Target
| Introduction | This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Product Overview | This product is a Rabbit antibody against the BARD1. It can be used for BARD1 detection in Western Blot, Co-IP. |
| Alternative Names | BRCA1 Associated RING Domain 1; RING-Type E3 Ubiquitin Transferase BARD1; EC 2.3.2.27; BARD-1; BARD1, ATBARD1, BREAST CANCER ASSOCIATED RING 1, REPRESSOR OF WUSCHEL1, ROW1 |
| UniProt ID | F4I442 |
See other products for " BARD1 "
| CBMOAB-36774FYA | Mouse Anti-Rhesus BARD1 Antibody (CBMOAB-36774FYA) |
| MO-AB-21326W | Mouse Anti-Chimpanzee BARD1 Antibody (MO-AB-21326W) |
| MO-AB-01803H | Mouse Anti-Frog bard1 Antibody (MO-AB-01803H) |
| MO-AB-07968R | Mouse Anti-Cattle BARD1 Antibody (MO-AB-07968R) |
| CBMOAB-25066FYC | Mouse Anti-Arabidopsis BARD1 Antibody (CBMOAB-25066FYC) |
| CBMOAB-67436FYA | Mouse Anti-Zebrafish bard1 Antibody (CBMOAB-67436FYA) |
For Research Use Only | Not For Clinical Use.
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