Cat: MOFY-0522-FY204
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse |
| Species Reactivity | Bovine |
| Format | Liquid |
| Buffer | PBS |
| Regulatory Status | For Research Use Only. Not For Clinical Use. |
| Shipping | Gel Pack |
| Storage | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
Application Information
| Application | RIPA, FC, WB |
| Application Notes | The optimal dilution should be determined by the end user. |
Target
| Introduction | Previous studies of monoclonal antibodies to the antigenic structure of the bovine leukemia virus (BLV) envelope glycoprotein (gp51) have identified three epitopes (F, G, H) that are directly associated with BLV infectivity, F, G, and H Individual mAbs were lost after treatment with reducing agents, indicating that these epitopes are conformational. Sequence comparison between BLV mutants and differential reactivity of urokinase or proteinase K gp51 fragments with monoclonal antibodies indicated that the NH2 portion of the env protein contains three structural determinants, F, G, and H. ELISA tests showed that the anti-F, -G, and -H monoclonal antibodies had the greatest reactivity against intact virions, while they exhibited poorer affinity for their respective epitopes when presented on purified protein. Therefore, an effective vaccine against BLV infection would include at least the identified gp51 region presented in its native structural configuration. |
| Product Overview | Mouse Anti-BLV gp51-G D-D Antibody (MOF032922W380) is a Mouse antibody against BLV gp51-G D-D. It can be used for BLV gp51-G D-D detection in RImmunoprecipitationA, Flow Cytometry, Western Blot. |
| Alternative Names | BLV gp51-G D-D'; Bovine Leukemia Virus (BLV) MAb gp51 D-D' |
Reference
For Research Use Only | Not For Clinical Use.