Mouse Anti-C. elegans AIR1 Antibody (CBMOAB-00452HCB)
Cat: CBMOAB-00452HCB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
| Size: | |
| Conjugate: | |
| Inquiry |
- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans) |
| Clone | MO00452HB |
| Specificity | This antibody binds to C. elegans AIR1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Cytoskeleton |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Component of the TRAMP (TRF4) and TRAMP5 complexes which have a poly(A) RNA polymerase activity and are involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information. Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates like cryptic transcripts generated by RNA polymerase II and III, or hypomethylated pre-tRNAi-Met. Both complexes polyadenylate RNA processing and degradation intermediates of snRNAs, snoRNAs and mRNAs that accumulate in strains lacking a functional exosome. AIR1 also inhibits the methylation of NPL3 mediated by HMT1 through its interaction with HMT1. |
| Product Overview | Mouse Anti-C. elegans AIR1 Antibody is a mouse antibody against AIR1. It can be used for AIR1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Aurora / Ipl1-related protein kinase 1; Protein AIR-1; air-1 AIR-1 |
| Gene ID | 179202 |
| UniProt ID | G5EDL3 |
| Protein Refseq | The length of the protein is 326 amino acids long. The sequence is show below: MSGKENTAPVIDDQKAEVISLTEDSRPQRVDQAREESCWSLDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVADHSKRHTLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLVDIMAHPWIKEMKQREDIEVPLFISTLTKSSRNNSTANQ. |
See other products for " AIR1 "
| CBMOAB-1957FYC | Mouse Anti-Arabidopsis AIR1 Antibody (CBMOAB-1957FYC) |
| CBMOAB-00196CR | Mouse Anti-Yeast AIR1 Antibody (CBMOAB-00196CR) |
For Research Use Only | Not For Clinical Use.
Online Inquiry