Mouse Anti-C. elegans CED12 (clone MO01250HB) Antibody (CBMOAB-01250HCB)


Cat: CBMOAB-01250HCB
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneMO01250HB
SpecificityThis antibody binds to C. elegans CED12.
FormatLyophilized
StorageStore at 4°C: short-term (1-2 weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionInvolved in programmed apoptosis and necrosis. Required for the cell corpse engulfment process. Has roles in the formation of actin halos and distal tip cell migration (PubMed:11703939, PubMed:11703940, PubMed:11146658, PubMed:11595183, PubMed:14645848, PubMed:15620647, PubMed:15247908, PubMed:15744306, PubMed:21490059). Negatively regulates the unc-6/Netrin receptor unc-5 to control distal tip cell migration along the anterior-posterior axis of the body (PubMed:26292279). Plays no role in amphid axon outgrowth (PubMed:12297102).
Product OverviewMouse Anti-C. elegans CED12 (clone MO01250HB) Antibody (CBMOAB-01250HCB) is a mouse antibody against CED12. It can be used for CED12 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCell death abnormality protein 12; ced-12
UniProt IDQ8STE5
Protein RefseqThe length of the protein is 731 amino acids long. The sequence is show below: MAFHMPLKELQPVDTSLPEHVVKGAVVIDKEFTIWNHRAVIPSNALHTVFITINLLEQKLTDVVKMAARSMNLSEDDSYGLMADKPKRFITDDNLNSLGSGFILTLCASPDHYVKRITEILTEGNNISQMENAVKTLDEFSLDPALIEAFYRCSSLELLFSLIRDDRVCMSSTLLSTCLRALSSMLELAVGDFTWKSVPNDVVVSMASLVTGKAKREEANTLLAALQMLEQLVIGDDTTRDWILEEVPIETLIRHVEKSDERIALCALSLMNSMIRRCPDDEKRFELIKSLEVVPFRNAVHSSLLRGGGGVRNLNAIEQLVEVQRSLISAYETSPPTDAEVQKILDIESSEDVSEEIREMWKSQIGEHRCGRLAAISMVQFAEKSPQDLRMLISENTMRIEGGKWQLIPMWMRCCDIAAELFRVIPGRDELDRLIVVLFSTETPFPAVFACIVHLFHRTWREMQAKGGEMEKVACVVLEQLRHVLKRREIQDVEELSADLETFSYRAMQEIWREEQLGKENIQLHSEAVIQLKSKLRPKMEELVRINHLNYLKLGAVFRKPQKSKSLAKLAFWHWKLDASEKMLTITGCDGENYVEGVQRDDIRQVWIKDIADVTNNDEIDRKASSSRFTSSPSTQMLRGIRVQLKTTNDMKEGEVLMALTSDETQSVIWLEGLAELIGSKAVKSETDAMVERMLKMELRVRLLNVKLTNPEEKPEIPPIPDDIKSFISKF.
For Research Use Only | Not For Clinical Use.

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