Mouse Anti-C. elegans DAD1 Antibody (CBMOAB-02474HCB)
Cat: CBMOAB-02474HCB
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | C. elegans (Caenorhabditis elegans) |
Clone | MO02474HB |
Specificity | This antibody binds to C. elegans DAD1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Endoplasmic reticulum; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. |
Product Overview | Mouse Anti-C. elegans DAD1 Antibody is a mouse antibody against DAD1. It can be used for DAD1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1; Oligosaccharyl transferase subunit dad-1; EC 2.4.99.18; Defender against cell death 1; Protein dad-1; dad-1 |
UniProt ID | P52872 |
Protein Refseq | The length of the protein is 113 amino acids long. The sequence is show below: MAAQVVPVLSKLFDDYQKTTSSKLKIIDAYMTYILFTGIFQFIYCLLVGTFPFNSFLSGFISTVTSFVLASCLRMQVNQENRSEFTAVSTERAFADFIFANLILHLVVVNFLG. |
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For Research Use Only | Not For Clinical Use.
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