Cat: CBMOAB-00074HCB
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans) |
| Clone | MO00074HB |
| Specificity | This antibody binds to C. elegans GSNL1. |
| Format | Lyophilized |
| Storage | Store at 4°C: short-term (1-2 weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Cytoskeleton; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping) (PubMed:18640981, PubMed:20392036). Binds actin but does not nucleate actin polymerization, albeit slows down elongation by blocking the barbed ends (PubMed:18640981, PubMed:20392036). By promoting actin depolymerization, required for the elimination of presynaptic components downstream of the egl-1, ced-4 and ced-3 apoptotic pathway during larval development (PubMed:26074078). |
| Product Overview | Mouse Anti-C. elegans GSNL1 (clone MO00074HB) Antibody (CBMOAB-00074HCB) is a mouse antibody against GSNL1. It can be used for GSNL1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Gelsolin-like protein 1; gsnl-1; |
| Gene ID | 179328 |
| UniProt ID | Q21253 |
| Protein Refseq | The length of the protein is 475 amino acids long. The sequence is show below: MGGTSLDPALAEIGKKNGLLVWRINKFVLEPVPEVDHGVFYIGDAYIALYQKYDGCWDVHFWLGKNASTDEIGVAAIKTVEIDDSLGGIPTQHREIQNYESPLFLSYFPDGIRYVSGGYESGYRHVDDQFKNWKPHLFHCKGKRNVRCTEVECEVNSLNLGDVFILDLGKDLYVWMPPESGRLERIKGMARAKNIADHERMGIPKVHILDDVEWDNDSTFWSYFGGVSSVRKVSKGKDDDDNYWKRLTEQITLWKVSDASGAAKVSMVSQGENIRKEQLDPKDAFILDAINGGIFVWIGHECTLEERSKALIWGQNYLKQHHLPRWTQVTRVLESAESTQFTQWFRDWVDEKKKNTFTPLLFQVSDESGLLHVEEIANFTQEDLDGDDVMILDALNSIYVWVGANANANEKKEALNTAKLYLEKDKLPRHKKTAIDTIFQGKEPPTFKKFFPSWDDNLFKNEVRSVQNMRRLLFH. |
For Research Use Only | Not For Clinical Use.