Cat: CBMOAB-06905HCB
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans) |
| Clone | MO06905HB |
| Specificity | This antibody binds to C. elegans MTM3. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Preferentially dephosphorylates phosphatidylinositol 3-phosphate (PI3P), and has some activity towards phosphatidylinositol 3,5-bisphosphate (PI35P) (PubMed:18393358, PubMed:25124690). May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues (By similarity). Positively regulates autophagy and is recruited to autophagosomes by PI3P where it catalyzes PI3P turnover to promote autophagosome maturation (PubMed:25124690). Thought to have a role in maintenance of muscle function (PubMed:18393358). Involved in locomotion and lifespan determination (PubMed:18393358). |
| Product Overview | Mouse Anti-C. elegans MTM3 (clone MO06905HB) Antibody (CBMOAB-06905HCB) is a mouse antibody against MTM3. It can be used for MTM3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Myotubularin-related protein 3; ceMTM3; EC 3.1.3.48; Myotubularin homologous protein 1; ceMTMH1; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; EC 3.1.3.95; Phosphatidylinositol-3-phosphate phosphatase; EC 3.1.3.64; mtm-3 |
| UniProt ID | Q22712 |
| Protein Refseq | The length of the protein is 1006 amino acids long. The sequence is show below: MTVTSSAAIDIGGGGGGRRSDRLDSDRTSEDMSFIASPANESFQIGASFVDVQNESSGSIDTATATLHELNYTFGMPPVTEESENMPQNYETVVELLPGEERAPINKLTEFPIEGGSLFVTNFRIVVILKDKEVEEALRFLVFPLQDIEQIDLAIPAFIHLSLKIGRMFTICFKTAEDAALVHKILYTAFQRLNRPISSIYTSRPQDWTSKNTDNPMQSLNAFAWKFSEAVDELDRDGKLPSWLLRADSVAQEITHIDFNRLGMSEHFQISSVNENFEVCPTYPEKIIVPKGITDDDIRKGAPYRSIGRFPAVIWRCRKTRAVLMRSSQPQVGILSWRNPTDEKIIEEAVKASRIEGEEKKQFIIMDARGYTSAFANRARSGGFENTEYYQQAKLEFLGLPNIHAVRGSFNNVRTMLHNLGPNEQLLTSLQTTGWLLNLSNLLVNAANCADHLSKGHSVLVHCSDGWDRTTQVTTLAKIMLDEYYRTVKGFEELIRRDWIAFGHKLYDRQLVAFGNWGTSDERSPVFLQFLEAVRHLQREQPTLFQFTHAYLIKLAKHAYSGLFGSFLFNSHKERREAMEKCKGTLVDIWRFIGPHNEEYVNQSFDEHYTGAVKPVNVSVINLRVWHEVFADEEEHYTQIFSPKEERPLSGCTTPMNTSTSTNLVKSKSSESINSLNVDGSAKESSQQHPTCSTTPSDNTNSLPMSTSFIQQSLYQPKVRGVAAIDRDGVIRFEDDEQAMLRKKNKLRAEEIRRKDEKIEELRRRAVLDTNKVSPGQRQSYSESDVETTGTLERVMSDVSMVDPVNELPHFKPNTTWEGESGHCAYCKKEFNKLSVYVEDRQHHCRNCGRVVCEDCSKNRFSVIEEGKSVQKRACDSCYDSMHETDLKLSSSSTTTTSSSTKIENDSNVPGLDNNSDNVSENVSENAIPDIIVEEKEAEDPIKEAESPSKETKCPKTLRNFISFSPKSSMRKNKVHSRDPLKSIDEGSSSQQAESDDVLDVNEQPL. |
Reference
For Research Use Only | Not For Clinical Use.