Rabbit Anti-CASP3 Antibody (MOFAB-043W)


Cat: MOFAB-043W
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Specifications

Host speciesRabbit
Species ReactivityHuman, Mouse, Rat, Rabbit, Chicken, Guinea Pig, Hamster, Monkey, Sheep, Bovine, Canine, Porcine, Yeast
SpecificityThis antibody recognizes caspase-3 in human, mouse, rat, bovine, canine, chicken, guinea pig, hamster, monkey, pig, rabbit and yeast.
ImmunogenFull-length human caspase-3.
FormatLiquid or Lyophilized
BufferPBS, 50% glycerol
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A

Application Information

ApplicationWB, IHC
Application NotesIB: 1-5ug/ml A band of ~36kDa is detected.
IHC: 10ug/ml
The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Product OverviewThe CASP3 antibody is used as Apoptosis.
Alternative NamesCaspase 3; Caspase 3, Apoptosis-Related Cysteine Peptidase; Caspase 3, Apoptosis-Related Cysteine Protease; SREBP Cleavage Activity 1; Cysteine Protease CPP32; Protein Yama; EC 3.4.22.56; Apopain; CASP-3; Caspase-3
Gene ID836
UniProt IDP42574
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MO-AB-36856WMouse Anti-Goat CASP3 Antibody (MO-AB-36856W)
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CBMOAB-25710FYCMouse Anti-Arabidopsis CASP3 Antibody (CBMOAB-25710FYC)
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MO-AB-16426WMouse Anti-Chimpanzee CASP3 Antibody (MO-AB-16426W)
MO-AB-34481WMouse Anti-Ferret Casp3 Antibody (MO-AB-34481W)
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For Research Use Only | Not For Clinical Use.
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