Mouse Anti-CASP6 Antibody (MOFY-0722-FY50)


Cat: MOFY-0722-FY50
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Specifications

Host speciesMouse
Species ReactivityBovine
ImmunogenRecombinant Caspase 6 (CASP6)
FormatLiquid or Lyophilized
Buffer0.01M PBS, pH7.4, 50% glycerol
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A or G

Application Information

ApplicationWB, IHC, ICC, IP
Application NotesWB: 0.5-2 µg/mL
IHC: 5-20 µg/mL
ICC: 5-20 µg/mL
The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015]
Alternative NamesCaspase 6; Caspase 6, Apoptosis-Related Cysteine Peptidase; Caspase 6, Apoptosis-Related Cysteine Protease; EC 3.4.22.59; MCH2; Apoptotic Protease MCH-2;
For Research Use Only | Not For Clinical Use.
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