Mouse Anti-Cattle ABHD12 Antibody (MO-AB-06789R)
Cat: MO-AB-06789R
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Cattle (Bos taurus) |
| Clone | MO06789R |
| Specificity | This antibody binds to Cattle ABHD12. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Other locations; Endoplasmic reticulum |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
| Product Overview | Mouse Anti-Cattle ABHD12 Antibody is a mouse antibody against ABHD12. It can be used for ABHD12 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Monoacylglycerol lipase ABHD12; EC 3.1.1.23; 2-arachidonoylglycerol hydrolase; Abhydrolase domain-containing protein 12; ABHD12 |
| UniProt ID | Q08DW9 |
| Protein Refseq | The length of the protein is 398 amino acids long. The sequence is show below: MRKRTEPVALEHERRTASGSPSAGPAAAALDADCRLKQNLCLAGPGPAEPRCAADAGMKRALGRRKGLCFRLRKILFFVLGLYVAIPFLIKLCPGIQAKLIFLNFVRVPYFIDLKRPQDQGLNHTCNYYLQPEEDVTIGVWHTVPTVWWKNAQGKDQMWYEDALSSSHPIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKVRSGDNPVYIWGHSLGTGVATNL. |
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For Research Use Only | Not For Clinical Use.
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