Mouse Anti-Cattle HRG Antibody (MO-AB-13804R)
Cat: MO-AB-13804R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO13804R |
Specificity | This antibody binds to Cattle HRG. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Extracellular region or secreted; Lysosome; Endosome; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions. Inhibits rosette formation. Acts as an adapter protein and implicated in regulating many processes such as immune complex and pathogen clearance, cell adhesion, angiogenesis, coagulation and fibrinolysis. Mediates clearance of necrotic cells through enhancing the phagocytosis of necrotic cells in a heparan sulfate-dependent pathway. This process can be regulated by the presence of certain HRG ligands such as heparin and zinc ions. Binds to IgG subclasses of immunoglobins containing kappa and lambda light chains with different affinities regulating their clearance and inhibiting the formation of insoluble immune complexes. Binds T-cells and alters the cell morphology Modulates angiogenesis by blocking the CD6-mediated antiangiongenic effect of thrombospondins, THBS1 and THBS2 (By similarity). Tethers plasminogen to the cell surface. |
Product Overview | Mouse Anti-Cattle HRG Antibody is a mouse antibody against HRG. It can be used for HRG detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Histidine-rich glycoprotein; HRG |
UniProt ID | F1MKS5 |
Protein Refseq | The length of the protein is 536 amino acids long. The sequence is show below: MKVLTAALLSILLITQQCSCAVNPTGCDAVEPVAVRALDLINKGRWDGYLFQLLRVADAHLDKVESIAVYYLVLDVKESDCPVLSRKHWDDCELDVSRRPSETVIGQCKVIAITLLAGPEDLRVNDFNCTTSSVSSALTNTIDSPVLFDFFEDTELYRKQAEKALEKYQRENSDFAPFRVDKVKRAMRARGGEGTSYFLDFSVRNCSSHHFPRHSHIFGFCRADLFYDVEASDLETPKDIVTNCEVFNLKEHRNF. |
See other products for " HRG "
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CBMOAB-20763FYA | Mouse Anti-D. melanogaster Hrg Antibody (CBMOAB-20763FYA) |
For Research Use Only | Not For Clinical Use.
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