Mouse Anti-Cattle SIRPA Antibody (CBMOAB-00025FYA)

Cat: CBMOAB-00025FYA
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Host speciesMouse (Mus musculus)
Species ReactivityCattle (Bos taurus)
SpecificityThis antibody is binds to Cattle SIRPA.

Application Information

Application NotesAssay-dependent


IntroductionThe protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.
Product OverviewMouse Anti-Cattle SIRPA (clone F00025FYA) Antibody (CBMOAB-00025FYA) is a Mouse antibody against the SIRPA. It can be used for SIRPA detection in Flow Cytometry.
Alternative NamesSignal Regulatory Protein Alpha; CD172 Antigen-Like Family Member A; Inhibitory Receptor SHPS-1; Macrophage Fusion Receptor; PTPNS1; SHPS1; SIRP; P84; BIT; MFR; Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs; Brain Ig-Like Molecule With Tyrosine-Based Activation Motifs; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1; Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; Tyrosine Phosphatase SHP Substrate 1; Signal-Regulatory Protein Alpha-1; CD172a
Gene ID140885
UniProt IDP78324
For Research Use Only | Not For Clinical Use.

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