Mouse Anti-Chicken Cd14 Antibody (MO-AB-01043Y)
Cat: MO-AB-01043Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Chicken (Gallus gallus) |
Clone | MO01043Y |
Specificity | This antibody binds to Chicken Cd14. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Plasma membrane; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | CD14 (CD14 Molecule) is a Protein Coding gene. Diseases associated with CD14 include Mycobacterium Chelonae and Croup. Among its related pathways are Bacterial infections in CF airways and Development Slit-Robo signaling. Gene Ontology (GO) annotations related to this gene include lipopolysaccharide binding and lipoteichoic acid binding. Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL) and mediates the cytokine release induced by LDL. |
Product Overview | This product is a mouse antibody against Cd14. It can be used for Cd14 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | CD14 antigen; Cd14 |
UniProt ID | B0BL87 |
Protein Refseq | The length of the protein is 465 amino acids long. The sequence is show below: MRGAALLLLALGLQQAEGRCVFNRTQEYCLCYRLTQESAGSVIQCLAASAVEFQGGDLEKYADFPIEDLDDSTIDMLGSLQIRKIIFSDLLVPEVLLARVLRFFSYTQVQEMVFKSCSFVGRSSWADMAGRALPIVSLRFHNVTAAALAGREQDLSPLSRWLGALQELSVTASRLAVLPCAVGQALRALRSLDLARNSLGDDSLAPAFCQGAFTQLRVLSLRHNNLTSYSGVCGSVRLLGELQHLDLSHNALTAGTPSSPCQWPATLRIFNLSSAGLDHVLAPLPPALEVLDLSSNRLHAVDISLRSLQALFLSRNALPAAPSIRGCPALHTLHLDNNLIAELPRDEALLLEHLQDVAVAGNPFNCTCGGAGAVQALAAVGCLRQGWPQGYVCHAPARYQGVLLRDVPTSVLQCNPAAVLAPVCTGLALLCVAMAGGLLWARGARPRWLCGLGQREDACSGAEHL. |
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For Research Use Only | Not For Clinical Use.
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