Mouse Anti-Chicken NPR1 Antibody (MO-AB-03206Y)
Cat: MO-AB-03206Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Chicken (Gallus gallus) |
Clone | MO03206Y |
Specificity | This antibody binds to Chicken NPR1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Plasma membrane; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively). |
Product Overview | This product is a mouse antibody against NPR1. It can be used for NPR1 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Guanylate cyclase; EC 4.6.1.2; NPR1 |
UniProt ID | F1NDM7 |
Protein Refseq | The length of the protein is 876 amino acids long. The sequence is show below: MLELLSAALHLQIPGTASCTWPPSRTSKLCDRRVAVKVILVEGWHDLDNKDYDCWPLEKPDEYNMMDCGGLEMAWVQKPPETAVSGEFFNVTYAVFASDGFYQYAVQNGILSHSNASAAKEFCEEHECPASWKDANGENCCVHHANIHSCPLAFMGRGGICGPWIPDDGQIFTHTLSTAGKMSQRNWTSKVVLVHVGVTSLIAHIRVGRMQVALEAKTTVLPAVVCGDGFCEEEESCSICPADCGECPLSAYARIAIALPICLVCTGFIMTVMWFQYQKQKMLWDESWIIEFTCIKQDHILWTATGSVMSGPPAPSESNASCITVLSSCTAAANASKKQHFTQTGRYDGRTVAIKKIMKKAFTLSKSIRKEVKQVRELDHPNLCKFIGGCIEIPNVAIVTEYCPKGSLHDVLLNEDIPLNWGFRFSFATDIAQGMAYLHHHKMYHGRLKSNNCVIDDRWVCKIADYGLQLYRKEDSSEGYQQHLIQIYTAPEIHSLLDFEPNSMTDVYSYAIILLEIATRSDPMPKDDVPSSEHSWCLPLAELISGKAEDSCPCPTDYIELIRKCRKNNPVQRPTFEQIKKMLNKMNPNKVNPVDMMMTLMEKYSKHLEILVSERTQDLMHEKQKTDRLLYSMLPKQVADDLRQGKRAQAQSYLSATIFFSDIVGFTQLSSSSTPYQVVDLLNKLYTTFDEIIDNYDVYKVETIGDAYMVVSGVPKENGILHAGEIASMALDLVNVCKTFKIPHKPNTLLKIRAGIHSGAVVAGVVGTKMPRYCLFGDTVNTASRMESTSEALKIQCSSSAYQLLEQIGDYVLICRGNLQVKGKGDMVTYWLEGKKASATQKTVPNPSVTLQDPNRASFSLIPGVLQSDPVSSPSY. |
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For Research Use Only | Not For Clinical Use.
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