Mouse Anti-Chicken TARDBP Antibody (MO-AB-04292Y)
Cat: MO-AB-04292Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Chicken (Gallus gallus) |
Clone | MO04292Y |
Specificity | This antibody binds to Chicken TARDBP. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | TAR DNA-binding protein 43 (TDP-43, response to DNA-binding protein 43 kDa) is a protein encoded by the TARDBP gene in humans. TDP-43 has been shown to bind DNA and RNA, and has multiple functions in transcriptional suppression, pre-mRNA splicing and translation regulation. Recent work has characterized the binding sites of the entire transcriptome, revealing that thousands of RNAs in neurons are bound by TDP-43. TDP-43 was originally identified as a transcriptional repressor, which binds to chromosomally integrated transactivation response element (TAR) DNA and inhibits HIV-1 transcription. It is reported that it can also regulate the alternative splicing of CFTR gene and apoA-II gene. |
Product Overview | This product is a mouse antibody against TARDBP. It can be used for TARDBP detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | TAR DNA-binding protein 43; TARDBP |
UniProt ID | F1NBY1 |
Protein Refseq | The length of the protein is 414 amino acids long. The sequence is show below: MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPEAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDIKTGHSKGFGFVRFTDYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTADELQQFFAQYGEVVDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERGGRFGGNPGGFGNQGGFGNSRGGGGGLGNNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQPQGNMQREQNQGFSSGNNSYGGSNSGAAIGWGSASNAGSSSGFNGGFGSSMDSKSSGWGM. |
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For Research Use Only | Not For Clinical Use.
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