Mouse Anti-Chicken USP14 Antibody (MO-AB-04706Y)
Cat: MO-AB-04706Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Chicken (Gallus gallus) |
Clone | MO04706Y |
Specificity | This antibody binds to Chicken USP14. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Other locations; Cytosol; Nucleus |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation. |
Product Overview | This product is a mouse antibody against USP14. It can be used for USP14 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Ubiquitin carboxyl-terminal hydrolase; EC 3.4.19.12; USP14 |
UniProt ID | E1C4M6 |
Protein Refseq | The length of the protein is 505 amino acids long. The sequence is show below: PSGNAAPGSAPSAMPLFSVNVKWGKEKFDGVELNTDEPPMVFKAQLFALTGVQPARQKVMLRGGTLKDDDWGNIKIKDGMTLLMMGSADALPEEPIARPVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPEVKEALKRYGGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGDQGQYLQQDANECWGQMMRVLQQKLEGIEGDTVMETDSGATATASKKKSLIDQFFGIEIETVMKCTEAEEEEVTKGKENQLQLSCFISQEVKYLFTGLKLRLQEEITKLSPTLQRDALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPDLQEKMVSYRSKFKDLEDKKVNQQPKNLSKSDGAQKEVKYEPFSFPDDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRIEVIEDEAEQ. |
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For Research Use Only | Not For Clinical Use.
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