Mouse Anti-Cottonwood LSM3 Antibody (MO-AB-27789W)


Cat: MO-AB-27789W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityCottonwood (Populus deltoids)
CloneMO27789W
SpecificityThis antibody binds to Cottonwood LSM3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionComponent of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 snRNP, U4/U6.U5 snRNP, and free U6 snRNP). It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. It probably also is involved in degradation of nuclear pre-mRNA by targeting them for decapping. LSM3 binds specifically to the 3''-terminal U-tract of U6 snRNA. LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA. LSM3, probably in a complex that contains LSM2-LSM7 but not LSM1 or LSM8, associates with the precursor of the RNA component of RNase P (pre-P RNA) and may be involved in maturing pre-P RNA. LSM3 is required for processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
Product OverviewMouse Anti-Cottonwood LSM3 Antibody is a mouse antibody against LSM3. It can be used for LSM3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesSmall nuclear ribonucleoprotein
UniProt IDB9H7R8
Protein RefseqThe length of the protein is 97 amino acids long.
The sequence is show below: MASEEESAVKEPLDLIRLSLDERIYVKLRSDRELRGKLHAYDQHLNMILGDVEEIVTTVEIDDETYEEIVRTTRRTVPFLFVRGDGVILVSPPLRTA.
For Research Use Only | Not For Clinical Use.
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