Mouse Anti-D. melanogaster Best1 Antibody (CBMOAB-02375FYA)
Cat: CBMOAB-02375FYA
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Fruit fly (Drosophila melanogaster) |
Clone | MO02375FYA |
Specificity | This antibody binds to fruit fly Best1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Plasma Membrane; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms. |
Product Overview | Mouse Anti-D. melanogaster Best1 Antibody is a mouse antibody against Best1. It can be used for Best1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Bestrophin 1; Bestrophin 1, isoform A; Dbest; LP05915p; Best1 |
UniProt ID | Q9V3J6 |
Protein Refseq | The length of the protein is 721 amino acids long. The sequence is show below: MTITYTGEVATCRGFGCFLKLLLRWRGSIYKLVWLDLLAFLTIYYAINMVYRFGLNPAQKETFEAIVQYCDSYRELIPLSFVLGFYVSIVMTRWWNQYTSIPWPDPIAVFVSSNVHGQDERGRMMRRTIMRYVCLCLTMVLANVSPRVKKRFPGLNNLVEAGLLNDNEKTIIETMNKAFPRPSKHWLPIVWAASIITRARKEGRIRDDFAVKTIIDELNKFRGQCGLLISYDTISVPLVYTQVVTLAVYSYFLTCCMGQQWTDGKVVGNTTYLNKVDLYFPVFTTLQFFFYMGWLKVAESLINPFGEDDDDFEVNWMVDRNLQVSYLIVDEMHHDHPELLKDQYWDEVFPNELPYTIAAERFRENHPEPSTAKIEVPKNAAMPSTMSSVRIDEMADDASGIHFSAGNGKMRLDSSPSLVSVSGTLSRVNTVASALKRFLSRDDSRPGSATPSQDQPYKFPASASSASLSGAVVGSATSAGKPAGSLRITQQVIEEVDEQATITSMRANDPRPNVMDIFAQTSSGAGTSGPLQPPPAHSEPVDIPSRPPSYNRAQSQYEPNLFPPGGVDALLSTSAPAGGSPLLLSNAATAPSSPVGESSKSLYDPQKGASRETVESMDLRSSTDLLGDAAVQPEDEGDDFDKLKAEREKEKLMRQQKNLARTISTAPGMEATAVPMVPMVPVNVAVQQAQLQPVASSADLLAGGDQFSNSTMKSEDAINGS. |
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CBMOAB-67627FYA | Mouse Anti-Zebrafish best1 Antibody (CBMOAB-67627FYA) |
MO-AB-01288W | Mouse Anti-Rhesus BEST1 Antibody (MO-AB-01288W) |
MO-AB-51847W | Mouse Anti-Marmoset BEST1 Antibody (MO-AB-51847W) |
MORAB-027F | Anti-BEST1 Antibody (Cat MORAB-027F), Mouse IgG |
MO-AB-08058R | Mouse Anti-Cattle BEST1 Antibody (MO-AB-08058R) |
MO-AB-29237W | Mouse Anti-Dog BEST1 Antibody (MO-AB-29237W) |
CBMOAB-00900HCB | Mouse Anti-C. elegans BEST1 Antibody (CBMOAB-00900HCB) |
MO-AB-24121R | Mouse Anti-Pig BEST1 Antibody (MO-AB-24121R) |
For Research Use Only | Not For Clinical Use.
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