Mouse Anti-D. melanogaster Pabp2 Antibody (CBMOAB-27123FYA)
Cat: CBMOAB-27123FYA
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO27123FYA |
| Specificity | This antibody binds to fruit fly Pabp2. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product (PubMed:10481015). Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Binds to poly(A) and to poly(G) with high affinity (PubMed:10481015). May protect the poly(A) tail from degradation (By similarity). Plays a role in the positive regulation of alpha-1,3 fucosylation, possibly by cooperating with swm which regulates nuclear export of fucosyltransferase FucTA (PubMed:21203496). |
| Product Overview | Mouse Anti-D. melanogaster Pabp2 Antibody is a mouse antibody against Pabp2. It can be used for Pabp2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Polyadenylate-binding protein 2; PABP-2; Poly(A)-binding protein 2; dPABP2; Nuclear poly(A)-binding protein 1; Poly(A)-binding protein II; PABII; Polyadenylate-binding nuclear protein 1; Protein rox2; Pabp2; rox2 |
| UniProt ID | Q7KNF2 |
| Protein Refseq | The length of the protein is 224 amino acids long. The sequence is show below: MADEDITLNEDQLLESLEETNGEQETEIATEVEEEGSMQIDPELEAIKARVKEMEEEAEKIKQMQSEVDKQMAGGSTTGLATVPLSLEEKQEIDTRSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALAMNETLFRGRQIKVMSKRTNRPGLSTTNRFARGSFRGRGARVSRACCHSTFRGARRAMGYRGRANYYAPY. |
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For Research Use Only | Not For Clinical Use.
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