Mouse Anti-D. melanogaster Pex19 Antibody (CBMOAB-27479FYA)


Cat: CBMOAB-27479FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneMO27479FYA
SpecificityThis antibody binds to fruit fly Pex19.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPeroxisome

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
Product OverviewMouse Anti-D. melanogaster Pex19 Antibody is a mouse antibody against Pex19. It can be used for Pex19 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGM14611p; Pex19
UniProt IDQ8T9H4
Protein RefseqThe length of the protein is 292 amino acids long.
The sequence is show below: MSEEKKNGDELNDLLDSALQDFDKSGAGDQKEPSASSDVATTAGAEGSEDPDAFFIEQAKVLADRMNTLFGGPDTPSGDIPPLPQDPDQIMAGFKKMAEAAALTLSGENSATDEDVSKYSDSISQALKGLQEGSENLAAPASENDIASMFGSLNLEGAGEGDGNMFLPFMEGMMQSLLSAEILLPSIRELLEKYPKYLEENDAKLSAEDKERYQKQMELYKVIEGHLQSEKTEDSAAVKREKFRVVLDDMRKLQDYGQPPPEILAETGGDLPFGDPTAGVAAGGPGPQCPTM.
For Research Use Only | Not For Clinical Use.
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