Mouse Anti-D. melanogaster Tab2 Antibody (CBMOAB-32508FYA)
Cat: CBMOAB-32508FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO32508FYA |
| Specificity | This antibody binds to fruit fly Tab2. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants. |
| Product Overview | Mouse Anti-D. melanogaster Tab2 Antibody is a mouse antibody against Tab2. It can be used for Tab2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Transcription factor; Tab2 |
| UniProt ID | Q9NFL3 |
| Protein Refseq | The length of the protein is 831 amino acids long. The sequence is show below: MAATPPMPPGSNTHQLNGKTVGKGNPLAEAINQHFQRKKQNQHQSPNPSPNPNPNSPASRSGSYEQLELLDHATHPQQQQEASSGKAKPSCHCTNISIMHLFHEMKQEFPTIPDAIVTQCVNENCHQRENCIQMLRKELALHPIPVQSYPAKVLQQQQQQHHQNRQAKPPTPLKPSRIAPPQPEAVLSNGVATPPGVGSPHPDTQPRPRPTTLNLQRQFSTQLQQKIMQRQQRQQRDHQPAQLTPTSLSKPLRRAPPLPPPPKPKPGSFSNDSSCLTSPMSSSESELSLNAVPLSSPTSAAATAAAASAAIASTQQQPSPVRHRSVITLQPEPPYARDFRSIDFPPTTACTPRLPSPSSAASPSAPGGRKSFTSLNLTLRQPTGSAQSAIDITAGPAPSGQGSGITYSSVSFDARRGTQKNFQLTVTDEGSVFSAGSVRPRTLYATPCEPVTSVPANQQPPPPAAVVADGLGDADMTSDVFPYPTQEQNHIVASNYSNNHAVSDNNNIGISNSTDSSPTMPLYEGVMEECDREARAATIERQKQRRDKLANALRDNKKRLLVLEQEINILTEPVPVGESERLDRDIKQLTEDCNRLLDCLNEPQANGPGPAANPTNRQHLLPGSNASQQQPQQQPQPFPRQRQSARVQAPPSSLRLHSVPAAPNSQPVQDFGQHHSSAPTSACLTPQMQSQQQLLQLQQEPPPTYAQYYQFQQYLQQQRQQQLQQQMQQQQQLQQQMQQQQQPQPQQEEEFLSDSDVDEEEETLDSWACNMCTFRNHPQLNICEACENVRIQPGMIRIVPSGGGAAAAAATPPGSIEQQQQPSQQPYALHT. |
See other products for " TAB2 "
| MO-AB-49670W | Mouse Anti-Maize TAB2 Antibody (MO-AB-49670W) |
| CBMOAB-08483FYB | Mouse Anti-Zebrafish tab2 Antibody (CBMOAB-08483FYB) |
| MO-AB-65779W | Mouse Anti-Marmoset TAB2 Antibody (MO-AB-65779W) |
| MO-AB-13178W | Mouse Anti-Chimpanzee TAB2 Antibody (MO-AB-13178W) |
For Research Use Only | Not For Clinical Use.
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