Cat: MO-AB-28810W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Dog (Canis lupus familiaris) |
| Clone | MO28810W |
| Specificity | This antibody binds to Dog ACY1. |
| Format | Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. |
| Product Overview | Mouse Anti-Dog ACY1 (clone MO28810W) Antibody (MO-AB-28810W) is a mouse antibody against ACY1. It can be used for ACY1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Aminoacylase-1; EC 3.5.1.14; N-acyl-L-amino-acid amidohydrolase; ACY1 |
| UniProt ID | F1PHI4 |
| Protein Refseq | The length of the protein is 408 amino acids long. The sequence is show below: MASEGLEGEHPSVTLFRRYLRIRTVQPEPDYGAAVAFLEERAHQLGLGCQKVEVAPGYVVTILTWPGTNPRLSSLILNSHTDVVPVFKEHWSHDPFEAFKDAEGYIYARGAQDMKCVSIQYLEAVRRLKAEGRHFPRTIHMTFVPDEEVGGHKGMELFVQRPEFRALKAGFALDEGLANPTDAFTVFYSERSPWWVRITSTGNPGHGSRFIEDTAAEKLHKVVSSILTFREKERQRLQSNPHLKAGAVTSVNLTKLEGGVAYNVVPATMSASFDFRVAPDVELKAFEEQLQGWCQAAGDGVTFDFAQKWTESRVTSTDDSDPWWAAFSGACKDMNLTLEPEIFPAATDSRYLRAVGVPALGFSPMNLTPVLLHDHDERLHEAVFLRGVDIYTRLLPALASVPALPSDG. |
See other products for " ACY1 "
| MO-AB-06978R | Mouse Anti-Cattle ACY1 Antibody (MO-AB-06978R) |
| MO-AB-50412W | Mouse Anti-Marmoset ACY1 Antibody (MO-AB-50412W) |
| CBMOAB-00924FYA | Mouse Anti-D. melanogaster Acy1 Antibody (CBMOAB-00924FYA) |
| CBMOAB-00920FYA | Mouse Anti-D. melanogaster Acy1 Antibody (CBMOAB-00920FYA) |
| MO-AB-50415W | Mouse Anti-Marmoset ACY1 Antibody (MO-AB-50415W) |
| CBMOAB-64837FYA | Mouse Anti-Zebrafish acy1 Antibody (CBMOAB-64837FYA) |
| MO-AB-50411W | Mouse Anti-Marmoset ACY1 Antibody (MO-AB-50411W) |
| MO-AB-50414W | Mouse Anti-Marmoset ACY1 Antibody (MO-AB-50414W) |
| MO-AB-25679W | Mouse Anti-Chimpanzee ACY1 Antibody (MO-AB-25679W) |
| CBMOAB-63781FYA | Mouse Anti-Zebrafish acy1 Antibody (CBMOAB-63781FYA) |
For Research Use Only | Not For Clinical Use.