Mouse Anti-Drosha Antibody (CBMOAB-15186FYA)


Cat: CBMOAB-15186FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-15186FYA Monoclonal Fruit fly (Drosophila melanogaster), Rhesus (Macaca mulatta) WB, ELISA MO15186FYA 100 µg
CBMOAB-41214FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO41214FYA 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), Rhesus (Macaca mulatta)
CloneMO15186FYA
SpecificityThis antibody binds to fruit fly Drosha.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.
Product OverviewMouse Anti-D. melanogaster Drosha Antibody is a mouse antibody against Drosha. It can be used for Drosha detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesDrosha; EC 3.1.26.3; LD20030p; Ribonuclease; drosha
UniProt IDQ7KNF1
Protein RefseqThe length of the protein is 1327 amino acids long.
The sequence is show below: MYQPPLPPPPVQPAPPPPPPPPEEDLSPPGVGVPSHNYSSNESHSQSSKSLDYVYPETPAPYASSVPSYDPYQQPPAYGYEGYAYNEQAQKYGGQESHYQYQYPASGSSFLYESYKYPDRYPAYSSNYRPPSERQRYTSNSSSQGYHHYPGYSSGRRYEQRHDQEHRQIQDSRYAHEPRHGHYAHRQAKGSQHGYYGSAARNQVSDDYSPRGHHERERNETLEKTRAKPKVETERDRLLRQWCSNFCEKPEDYVKKMNALSEADAPVESWVRSSPAELYYERTKSENEVRGRARLQKLCTLFDEELLQRAKRVREKLPVYVPPPRKARRRVCKHKHKSEACSSSSSSDDDSDEDAFKIEQDCCMEELSRKVQHPQRVHADLWHNDAGEMNDGPLCRCSAKSRRIGIRHGIYPGETGYKLCDPNSNNAGKLFHYRISISPPTNFLTKTPTIIKHDEHEFLFEGFSLLSHVRLSDLPVCKVIRFNIEYTIEYEEEKMPENFTIHELDIFFKYLFHELLELVDFNLMPNLPSGNVEESCPAFHFFPRFVRDLPDNGKEVLAMVEVLRYLLDNSAQLVERQQLLHLNQISQSEWQNYVDFIKGMLVTKPGYKPCSLRVDQLDRNNSDLPECVDRETGISHPAIVHFGICHPQLSYAGNPEYQKAWREYVKYRHLMANMSKPSFKDKRKLEEKEQRLQEMRTQGRMKRNITVAISSEGFYRTGIMCDVVQHAMLIPVLTGHLRFHKSLDLLEESIGYRFKNRYLLQLALTHPSYKENYGTNPDHARNSLTNCGIRQPEYGDRKIHYMNTRKRGINTLVSIMSRFGKEHETVSNITHNERLEFLGDAVVEFLSSIHLFFMFPELEEGGLATYRAAIVQNQHLALLAKKLQLEEFMLYAHGSDLCHELELRHAMANCFEALMGALLLDGGIKVADEVFTDALFRQDEKLLSIWKNLPEHPLQEQEPLGDRSCIDSYRVLKELTKFEDSIGIKFKHIRLLARAFTDRSIGFTHLTLGSNQRLEFLGDTVLQLICSEYLYRHFPEHHEGHLSLLRSSLVNNRTQAVVCDDLGMPKYAVYANPKADLKTKDRADLLEAFLGALYVDKGLLYCEQFCHVCLFPRLQLFIMNQDWNDPKSKLQQCCLTLRTMDGGEPDIPYYKVVEASGPTNTRVYKVAVYFRSKRLATSSGSSIQQAEMNAAKQALENSRDLFPQLDHQKRVIAKSIKKQTGNELDNDSDRQHQEEKIKRPKYATPLQDESHLPKQYRMHENISSDELPEDEDFESTAPKSPTMPLRSNRSGSSSSSSSSDSDGSTSSPKCKRRLKKCSSVSSKSSLG.
For Research Use Only | Not For Clinical Use.
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