Mouse Anti-E. coli cpxP (EVGSGDNWHPGE) Antibody
Cat: MOXC-003W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
| Size: | |
| Conjugate: | |
| Inquiry |
- Product Details
Specifications
| Host species | Mouse |
| Species Reactivity | E. coli |
| Clone | XM03 |
| Immunogen | E. coli cpxP (EVGSGDNWHPGE) |
| Epitope | EVGSGDNWHPGE |
| Format | Liquid or Lyophilized |
| Buffer | 0.05 M Tris-HCl, pH 7.4, 100 mM glycine |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Protein A or G |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Acts as an auxiliary protein in the Cpx two-component envelope stress response system, helping modulate the Cpx response systems response to some inducers (PubMed:25207645, PubMed:16303867). Binds the periplasmic domain of sensor histidine kinase CpxA, inhibiting induction of the Cpx envelope stress response in the absence of inducer; overexpression decreases Cpx pathway activity (PubMed:16166523, PubMed:21317318). Some periplasmic stimulii (shown for P pili subunit PapE and probably 0.3 M NaCl) increase CpxP's susceptibility to DegP, leading to CpxP degradation, inducing the Cpx pathway (PubMed:16166523, PubMed:16303867). Aids in combating extracytoplasmic protein-mediated toxicity (PubMed:9473036, PubMed:16303867, PubMed:21239493). Overexpression leads to degradation by DegP of misfolded P pili subunits in the periplasm (tested using PapE) (PubMed:21239493). Inhibits autophosphorylation of CpxA in reconstituted liposomes by 50% but has no effect on phosphatase activity of CpxA (PubMed:17259177, PubMed:21239493). Has mild protein chaperone activity (PubMed:21317898, PubMed:21239493). |
| Product Overview | This product is a Mouse antibody against the cpxP. It can be used for cpxP antibody detection in ELISA, but Western Blot can be tested by the end of the user. |
| Alternative Names | Periplasmic protein CpxP; cpxP; yiiO; b4484 JW5558 |
| UniProt ID | P0AE85 |
See other products for " cpxP "
For Research Use Only | Not For Clinical Use.
Online Inquiry