Rabbit Anti-EDNRB Antibody


Cat: MO-NAB-00499W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Zebrafish (Danio rerio)
CloneNW0421
SpecificityThis antibody is binds to Human EDNRB and has cross reactivity with Zebrafish.
FormatLiquid or Lyophilized
BufferTBS, pH7.4, 1% BSA, 40% Glycerol.
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A purified
Cellular LocalizationCell membrane

Application Information

ApplicationWB, IP
Application NotesWestern Blot: 1:500-1:2000
Immunoprecipitation: 1:10-1:50

Target

IntroductionEndothelin receptor type B is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. A splice variant, named SVR, has been described; the sequence of the ETB-SVR receptor is identical to ETRB except for the intracellular C-terminal domain. While both splice variants bind ET1, they exhibit different responses upon binding which suggests that they may be functionally distinct.
Product OverviewThis product is a Rabbit antibody against the EDNRB. It can be used for EDNRB detection in Western Blot, Immunoprecipitation.
Alternative NamesEDNRB; Endothelin receptor type B
Gene ID1910(Human); 13618(Mouse)
UniProt IDP24530(Human); P48302(Mouse)
For Research Use Only | Not For Clinical Use.
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