Mouse Anti-FCGR3A Antibody (CBMOAB-42756FYA)
Cat: CBMOAB-42756FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
CBMOAB-42756FYA | Monoclonal | Rhesus (Macaca mulatta), Cattle (Bos taurus), Human (Homo sapiens), Primate, Rat (Rattus norvegicus) | WB, ELISA | MO42756FYA | 100 µg | ||
MO-AB-12459R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO12459R | 100 µg | ||
MO-AB-25792H | Monoclonal | Rat (Rattus norvegicus) | WB, ELISA | MO25792C | 100 µg | ||
MO-NAB-00182W | Monoclonal | Human (Homo sapiens), Primate, Rhesus (Macaca mulatta) | FC, IF, IHC, IP, Neut, SPR | 3G8 | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta), Cattle (Bos taurus), Human (Homo sapiens), Primate, Rat (Rattus norvegicus) |
Clone | MO42756FYA |
Specificity | This antibody binds to Rhesus FCGR3A. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Product Overview | Mouse Anti-Rhesus FCGR3A Antibody is a mouse antibody against FCGR3A. It can be used for FCGR3A detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | FCGR3A variant 3; FCGR3A |
UniProt ID | H9BMP9 |
Protein Refseq | The length of the protein is 290 amino acids long. The sequence is show below: MGGEAGERLFTSSCLVSLVPLGLRISVVTCPLQRGIMWQLLLPTALLLLVSAGMRAEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTRWFHNESLISSQTSSYFIAAARVNNSGEYRCQTSLSTLSDPVQLEVHIGWLLLQAPRWVFKEEESIHLRCHSWKNTLLHKVTYLQNGKGRKYFHQNSDFYIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQDLAVSSISSFFPPGYQVSFCLVMVLLFAVDTGLYFSVKKSVPSSTRDWEDHKFKWSKDPQDK. |
For Research Use Only | Not For Clinical Use.
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