Mouse Anti-FLT3 Antibody (CBMOAB-42986FYA)

Cat: CBMOAB-42986FYA

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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-42986FYA	Monoclonal	Rhesus (Macaca mulatta), Dog (Canis lupus familiaris), Marmoset, Zebrafish (Danio rerio)	WB, ELISA	MO42986FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 993 amino acids long. The sequence is show below: MPALARGGGRLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLGCALRPQSAGTVYEAATVEVDVSASITLQVLVDTPGNVSCLWVFKHSSLNCQPHFDVQNRGVVSMVILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLFTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGSYFEMSTYSTNRTMIRILFAFVSSVARNNTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKAFPCEQKALDDGYSVSKFCNHKHQPGEYIFHAENGDAQFTKMFTLNIRRKPQVLAEASASQASCSSDGYPLPSWTWKKCSDKSPNCTEDIPEGVWNRKANRKVFGQWVSSSTLNMSEAMKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDSISFYATIGVCLLFIVVLTMLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFRDCDYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSRDVQIHPHSDPISGLHGNSFHSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIRNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPHLTSFLGCQLEDAEEAMYQNVDGRVSERPHIYQNRRPFSREMDSGPLSPKAQVEDS.
CBMOAB-76664FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO76664FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 956 amino acids long. The sequence is show below: MHLGIKLLLVLLVLHWSSLKDGLTEAHPRCDTDGSTVRCTLEETDLMSSDPIKLDVTEGQVVEIYSACEQNSSNERKCLCYQRTNSSIHLLQCIEKLGNEKYSVICGNKTVTAVRATQRRPSVPVLKAILKAGSTNLAQLVCTSEGYPKPTLRWYGNSDDAEEGMTSSACKTESTLISYYSYLSKNPNQKCCASNALGEECTEVYHYDLNEEDKQKSQNIIYLKSGQSLLLRAAKKDLRNPGIKWHFNNTVIKGITSLQYYDWTEHLFIESVNMAHSGLYLCTSDTKTPRNCSTHVKVFEHDQIDILHLNENNSILAKNKTDFCFQSQVFSYPKARCYWITPNQTQIQCDETSQSNFTSTFKLCNTEPGQYQMKLETQEYSVMRNVSLCISDIPKITIRKNSSFTTCETESPLPVTVSWKTCPSHAKCDPEDWKEIAADQPEFTDSDQFCQKKIGFSRRHLKSEDHLIKCCITNVAGTGCSEKILLQTKSHTYYVICFLLIVILFMIIIALIIFIRVKKPKYQSQIQMIQMIGPNDNDYIYIDFREFKYDLKWEFPRENLELGNELGSGAFGMVVQATAYGISKPGVSVQVAVKMLKEKHQAVEKEALMSELKMLTHIGHHENIVNLLGACTGSGPVYLIFQYCCNGDLLNYLKSNRECFHKYLTDAFNKDRFRGLYHNFQQNRNSSEYVLSDNSQCLNVTPASKEQEKENDALLSSSISSGSPAEEMLECEDEHQEEELHSLTYDDLLSFSFQVAKGMQFLSAKNCIHRDLAARNVLVTHGRQVKIADFGLARDIEHDSNYVVRGNVRLPVKWMAPESIFKGIYTMESDIWAYGILLWEIFSLGVTPYPGVTVNNTFYRMIESGYHLEQPYYAAESVYKVMCRCWALNPVDRPCFSKIVAFMEKELAALEERLYYNVGGYSHDEITYQNAPVMPEDTPIVTDTHGSGAVRTEPPV.
MO-AB-30815W	Monoclonal	Dog (Canis lupus familiaris)	WB, ELISA	MO30815W		100 µg	Inquiry
Protein Refseq: The length of the protein is 993 amino acids long. The sequence is show below: MPALARRGGRLPLLVVFSAMIFEAITNQDLPVIKCVLINHKNNDSSLGLSSSYPTASEPPEDLGCALKPESTEAVYGAATVEVDMSASITLQVLVNTPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQSGATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESIPEPTVEWVFCDSQSESCKGESPAVVTKEESVLHELFGTDIRCCARNELGRECTKLFTIDLNQTPQTTPPQLFLKVGEPLWIRCKAVHINHGFGLTWELENKALEEGSYFEMSTYSTNRTMIRILFAFVSSVGRNDTGYYTCSSSEHPSKSALVTILEKGFINASKSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQSGLDDGYSISKFCNHKHQPGEYIFHAENDDAEFTKMFTLNIRRKPQVQANTSASQASCSSDGYPLPSWTWKKCSDKSPNCTEEITEGIWNKKANRKVFGQWTSSSTLNMSEAVKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNVSFYATVGLCLPFIAILTMLICHKYKKQFRYESQLQMVQVTGSLDNEYFYIDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTHLGNHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRNKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIQQDLDHISGLNGNSFQSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVIRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQSGFKMDQPFYATEEIYFIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNMDGHVSDRPSVYQNRRPYSREVDSGLLAPQAHVEES.
MO-AB-55546W	Monoclonal	Marmoset	WB, ELISA	MO55546W		100 µg	Inquiry
Protein Refseq: The length of the protein is 993 amino acids long. The sequence is show below: MPALARGGGRLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVMESPEDLGCALRPQSAGTVYEAAAVEVEASASITLQVLVNTPGNISCLWVFKHSSLHCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPTVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIDLNRSPQTTLPQLFLKVGEPLWIRCKAVHVNYEFGLTWELEDKALQEGSYFEMSTYSTNRTMIRILFAFVSSVGRNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYDIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLNDGYSISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNVRRKPQVLAEASESQASCSSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRRANRKVFGQWVSSSTLNVSEALRGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGFCLLFIVVLTMLICHKYKKQFRYESQMQMVQVTGSSDNEYCYVDFREYEYDLKWEFPRENLEFGQVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPSFQSHPNSSMPGSREVQIHQDSDPISGLHGNSLHSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCIHRDLAARNVLVTHGKVVKICDFGLARDIMNDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYRLIRNGFKMDQPFYATEEIYFIMQSCWAFDARKRPSFPNLTSFLGCQLADAEEAMYQNMDGRVSERPHTYQNRRPFSREMNSGPLSPQAQVEDS.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Rhesus (Macaca mulatta), Dog (Canis lupus familiaris), Marmoset, Zebrafish (Danio rerio)
Clone	MO42986FYA
Specificity	This antibody binds to Rhesus FLT3.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Endoplasmic reticulum; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
Product Overview	Mouse Anti-Rhesus FLT3 Antibody is a mouse antibody against FLT3. It can be used for FLT3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Tyrosine-protein kinase receptor; EC 2.7.10.1; FLT3
UniProt ID	F6Y6U1
Protein Refseq	The length of the protein is 993 amino acids long. The sequence is show below: MPALARGGGRLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLGCALRPQSAGTVYEAATVEVDVSASITLQVLVDTPGNVSCLWVFKHSSLNCQPHFDVQNRGVVSMVILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLFTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGSYFEMSTYSTNRTMIRILFAFVSSVARNNTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKAFPCEQKALDDGYSVSKFCNHKHQPGEYIFHAENGDAQFTKMFTLNIRRKPQVLAEASASQASCSSDGYPLPSWTWKKCSDKSPNCTEDIPEGVWNRKANRKVFGQWVSSSTLNMSEAMKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDSISFYATIGVCLLFIVVLTMLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFRDCDYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSRDVQIHPHSDPISGLHGNSFHSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIRNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPHLTSFLGCQLEDAEEAMYQNVDGRVSERPHIYQNRRPFSREMDSGPLSPKAQVEDS.

For Research Use Only | Not For Clinical Use.

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