Mouse Anti-Frog abcc5 Antibody (MO-AB-01128H)
Cat: MO-AB-01128H
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Frog (Xenopus laevis) |
| Clone | MO01128C |
| Specificity | This antibody binds to Frog abcc5. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants. |
| Product Overview | This product is a mouse antibody against abcc5. It can be used for abcc5 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | MGC68608 protein; abcc5; MGC68608 |
| UniProt ID | Q6PA36 |
| Protein Refseq | The length of the protein is 210 amino acids long. The sequence is show below: MKDLDLGVEYVIPSLGYRNVREQHNQDERKESQDFKYQKAKPQHVDCLDALEAAARAEGLPLDISVHSNLKILDEGHHKGKYHHGRNLLKPFRITSKHQHPVDNAGLFSFMTFSWLTPMARLAYKKGELFFEDVWPLSKHESSDVNSKRLEKLWLEEVTEKGADESSLRSVVWNFCRTRLIISIMCLMLTQLAGFIGPVSNFHPVSIAQS. |
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| MO-AB-50201W | Mouse Anti-Marmoset ABCC5 Antibody (MO-AB-50201W) |
For Research Use Only | Not For Clinical Use.
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