Mouse Anti-Frog H2B Antibody (MO-AB-04144H)


Cat: MO-AB-04144H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO04144C
SpecificityThis antibody binds to Frog H2B.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionHistone H2B is one of the core components of nucleosomes. The nucleosome is the smallest subunit of chromatin and consists of 147 DNA base pairs wrapped around the core histone octamer (histone H2A, histone H2B, histone H3, and histone H4). Histone H1 is a linker histone that exists at the interface between the nucleosome core and the DNA entry/exit point; it is responsible for building higher-order chromatin structures. Chromatin undergoes a variety of chemical modifications, including post-translational modifications of histones and methylation of cytosine residues in DNA. The reported histone modifications include acetylation, methylation, phosphorylation, ubiquitination, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; they play a major role in regulating gene expression.
Product OverviewThis product is a mouse antibody against H2B. It can be used for H2B detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesHistone H2B; H2B
UniProt IDQ92131
Protein RefseqThe length of the protein is 126 amino acids long.
The sequence is show below: MSDPAKSAPAAKKGSKKAVTKTQKKDGKKRRKSRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLAHYNKRSTITSREIQTAGRLLLPGELAKHAVSEGTKAVTKYTSAK.
For Research Use Only | Not For Clinical Use.
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