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- Product Details
|Host species||Mouse (Mus musculus)|
|Species Reactivity||Frog (Xenopus laevis)|
|Specificity||This antibody binds to Frog nr3c1.|
|Storage||Store at 4°C: short-term (1-2 weeks)|
Store at -20°C: long-term and future use
|Purity||> 90% was determined by SDS-PAGE|
|Purification||Purified with Protein A or G affinity chromatography|
|Application Notes||ELISA: 1:1000-1:3000|
Other applications are to be developed. The optimal dilution should be determined by the end user.
|Introduction||This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).|
|Product Overview||This product is a mouse antibody against nr3c1. It can be used for nr3c1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.|
|Alternative Names||XGR protein; nr3c1; xGR|
|Protein Refseq||The length of the protein is 776 amino acids long.|
The sequence is show below: MDPKDLLKPSSGSPAVRGSPHYNDKPGNVIEFFGNYRGGVSVSVSASCPTSTASQSNTRQQQHFQKQLTATGDSTNGLNNNVPQPDLSKAVSLSMGLYMGESDTKVMSSDIAFPSQEQIGISTGETDFSLLEESIANLQAKSLAPDKLIEISEDPGGFKCDISAQPRPSMGQGGSNGSSSTNLFPKDQCTFDLLRDLGISPDSPLDGKSNPWLDPLFDEQEAFNLLSPLGTGDPFFMKSEVLSEGSKPLSLEDGTQRLGDHAKDMLLPSADLPISQVKTEKEDYIELCTPGVVKQEKFGPVYCVGNFSGSGLFGNKSSAISVHGVSTSGGQMYHYDLNTATISQQDVKPVFNLGSPGTSIAEGWNRCHGSGNDTAASPGNVNFPNRSVFSNGYSSPGIRSDASPSPSTSSTSTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQSTTATARESPETSMTRTLVPASVAQLTPTLISLLEVIEPEVLYSGYDSSIPDTTRRLMSSLNMLGGRQVVSAVRWAKAIPGFRNLHLDDQMTLLQYSWMFLMVFALGWRSYKQTNGSILYFAPDLVITEDRMHLPFMQERCQEMLKIAGEMSSLQISYDEYLCMKVLLLMCTIPKEGLKSHALFEEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVAENLLAFCFLSFLDKSMSIEFPDMLSEIISNQIPKYSSGNLKKLLFHQK.
See other products for " NR3C1 "
|MOFAB-122W||Sheep Anti-NR3C1 Antibody (MOFAB-122W)|
|MO-AB-08996Y||Mouse Anti-Rabbit NR3C1 Antibody (MO-AB-08996Y)|
|MO-AB-15328W||Mouse Anti-Chimpanzee NR3C1 Antibody (MO-AB-15328W)|
|MO-AB-08997Y||Mouse Anti-Rabbit NR3C1 Antibody (MO-AB-08997Y)|
|MO-AB-01075R||Mouse Anti-Medaka nr3c1 Antibody (MO-AB-01075R)|
|MO-AB-27131W||Mouse Anti-Chimpanzee NR3C1 Antibody (MO-AB-27131W)|
|CBMOAB-89901FYA||Mouse Anti-Zebrafish nr3c1 Antibody (CBMOAB-89901FYA)|
|CBMOAB-89902FYA||Mouse Anti-Zebrafish nr3c1 Antibody (CBMOAB-89902FYA)|
|MO-AB-16365Y||Mouse Anti-Sheep NR3C1 Antibody (MO-AB-16365Y)|
|MO-AB-27837R||Mouse Anti-Pig NR3C1 Antibody (MO-AB-27837R)|