Mouse Anti-GNE Antibody (CBMOAB-43771FYA)


Cat: CBMOAB-43771FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-43771FYA Monoclonal Rhesus (Macaca mulatta), Hamsters (Cricetinae), Marmoset, Pig (Sus scrofa), Zebrafish (Danio rerio) WB, ELISA MO43771FYA 100 µg
CBMOAB-78187FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO78187FYA 100 µg
MO-AB-03733W Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO03733W 100 µg
MO-AB-26152R Monoclonal Pig (Sus scrofa) WB, ELISA MO26152R 100 µg
MO-AB-43191W Monoclonal Hamsters (Cricetinae) WB, ELISA MO43191W 100 µg
MO-AB-56132W Monoclonal Marmoset WB, ELISA MO56132W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Hamsters (Cricetinae), Marmoset, Pig (Sus scrofa), Zebrafish (Danio rerio)
CloneMO43771FYA
SpecificityThis antibody binds to Rhesus GNE.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.
Product OverviewMouse Anti-Rhesus GNE Antibody is a mouse antibody against GNE. It can be used for GNE detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGNE
UniProt IDF6PS62
Protein RefseqThe length of the protein is 722 amino acids long.
The sequence is show below: MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDIIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY.
For Research Use Only | Not For Clinical Use.
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