Mouse Anti-GSTM2 Antibody (CBMOAB-44206FYA)


Cat: CBMOAB-44206FYA
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Lot Number

  • Product List
  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-44206FYA Monoclonal Rhesus (Macaca mulatta), Cattle (Bos taurus), Guinea pig (Cavia porcellus), Marmoset, Rat (Rattus norvegicus) WB, ELISA MO44206FYA 100 µg
CBMOAB-60161FYC Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO60161FYC 100 µg
MO-AB-13408R Monoclonal Cattle (Bos taurus) WB, ELISA MO13408R 100 µg
MO-AB-26152H Monoclonal Rat (Rattus norvegicus) WB, ELISA MO26152C 100 µg
MO-AB-41776W Monoclonal Guinea pig (Cavia porcellus) WB, ELISA MO41776W 100 µg
MO-AB-56455W Monoclonal Marmoset WB, ELISA MO56455W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cattle (Bos taurus), Guinea pig (Cavia porcellus), Marmoset, Rat (Rattus norvegicus)
CloneMO44206FYA
SpecificityThis antibody binds to Rhesus GSTM2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual''s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
Product OverviewMouse Anti-Rhesus GSTM2 Antibody is a mouse antibody against GSTM2. It can be used for GSTM2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGlutathione S-transferase M2; GSTM2
UniProt IDA0A023JBX5
Protein RefseqThe length of the protein is 218 amino acids long.
The sequence is show below: MSMTLGYWNIRGLAHSIRLLLEYTGSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGETEKEKIREDILENQLMDNRMQLARLCYDPDFEKLKPEYLEGLPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK.
For Research Use Only | Not For Clinical Use.
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