Cat: MO-MMB-0689
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Budding Yeast |
| Immunogen | A peptide including the phosphoserine 129 of histone H2A in budding yeast. |
| Format | Liquid |
| Buffer | 30% Glycerol |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Application Information
| Application | ChIP, WB |
| Application Notes | WB: 1:500-1:2000 The optimal dilution should be determined by the end user. |
Target
| Introduction | Histone H2A is one of the core components of nucleosomes, which are the basic building blocks of chromatin. Unlike mammals that have a unique DNA damage response to histone H2A variant H2AX, budding yeast histone H2A contains an SQ motif at the C-terminus, which is phosphorylated by Mec1 and Tel1 kinases in response to DNA double-strand breaks. Like mammalian H2AX phosphorylation, yeast histone H2A phosphorylation at serine 129 is necessary for effective repair of DNA double-strand breaks. |
| Alternative Names | H2AS129ph; Histone H2AS129ph |
Reference
For Research Use Only | Not For Clinical Use.