Anti-H2AS129ph Antibody (Cat MO-MMB-0689), Rabbit IgG

Cat: MO-MMB-0689
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  • Product Details


Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityBudding Yeast
ImmunogenA peptide including the phosphoserine 129 of histone H2A in budding yeast.
Buffer30% Glycerol
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Application Information

ApplicationChIP, WB
Application NotesWB: 1:500-1:2000
The optimal dilution should be determined by the end user.


IntroductionHistone H2A is one of the core components of nucleosomes, which are the basic building blocks of chromatin. Unlike mammals that have a unique DNA damage response to histone H2A variant H2AX, budding yeast histone H2A contains an SQ motif at the C-terminus, which is phosphorylated by Mec1 and Tel1 kinases in response to DNA double-strand breaks. Like mammalian H2AX phosphorylation, yeast histone H2A phosphorylation at serine 129 is necessary for effective repair of DNA double-strand breaks.
Alternative NamesH2AS129ph; Histone H2AS129ph


For Research Use Only | Not For Clinical Use.

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