Cat: MO-MMB-0699
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Budding Yeast, Human (Homo sapiens) |
| Immunogen | This Histone H3 acetyl Lys27 antibody is raised against peptides including the acetyl lysine 27 of histone H3. |
| Format | Liquid or Lyophilized |
| Buffer | 10 mM Sodium pH ospH ate, pH 7.5, 150 mM NaCl, 30% glycerol |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Protein A purified |
Application Information
| Application | ChIP, ChIP-Seq, Native ChIP, WB, IF, IHC(P), PLA |
| Application Notes | ChIP: 10 µg per ChIP ChIP-Seq: 5 µg each IF: 1-5 µg/mL WB: 0.1-1 µg/mL The optimal dilution should be determined by the end user. |
Target
| Introduction | Histone H3 is one of the core components of nucleosomes. The nucleosome is the smallest subunit of chromatin and consists of 147 DNA base pairs wrapped around the core histone octamer (histone H2A, histone H2B, histone H3, and histone H4). Histone H1 is a linking histone that exists at the interface between the nucleosome core and DNA entry/exit points; it is responsible for building higher-order chromatin structures. Chromatin undergoes a variety of chemical modifications, including post-translational modifications of histones and methylation of cytosine residues in DNA. The reported histone modifications include acetylation, methylation, phosphorylation, ubiquitination, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; they play a major role in regulating gene expression. |
| Alternative Names | H3K27ac; Histone H3K27ac |
Reference
See other products for " H3K27ac "
| MO-DKB-0252RA | Rabbit Anti-H3K27ac Antibody (MO-DKB-0252RA) |
| MO-MMB-0700 | Anti-H3K27ac Antibody (Cat MO-MMB-0700), Rabbit IgG |
For Research Use Only | Not For Clinical Use.