Mouse Anti-HEXB Antibody (CBMOAB-44499FYA)


Cat: CBMOAB-44499FYA
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Lot Number

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  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-44499FYA Monoclonal Rhesus (Macaca mulatta), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Marmoset, O. anatinus (Ornithorhynchus anatinus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries), Zebrafish (Danio rerio) WB, ELISA MO44499FYA 100 µg
CBMOAB-79383FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO79383FYA 100 µg
MO-AB-06551Y Monoclonal O. anatinus (Ornithorhynchus anatinus) WB, ELISA MO06551Y 100 µg
MO-AB-08019W Monoclonal Cat (Felis catus) WB, ELISA MO08019W 100 µg
MO-AB-08347Y Monoclonal Rabbit (Oryctolagus cuniculus) WB, ELISA MO08347Y 100 µg
MO-AB-13637R Monoclonal Cattle (Bos taurus) WB, ELISA MO13637R 100 µg
MO-AB-15628Y Monoclonal Sheep (Ovis aries) WB, ELISA MO15628Y 100 µg
MO-AB-16236W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO16236W 100 µg
MO-AB-26312R Monoclonal Pig (Sus scrofa) WB, ELISA MO26312R 100 µg
MO-AB-31108W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO31108W 100 µg
MO-AB-34884W Monoclonal Ferret (Mustela Putorius Furo) WB, ELISA MO34884W 100 µg
MO-AB-56697W Monoclonal Marmoset WB, ELISA MO56697W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Marmoset, O. anatinus (Ornithorhynchus anatinus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries), Zebrafish (Danio rerio)
CloneMO44499FYA
SpecificityThis antibody binds to Rhesus HEXB.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionHexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product OverviewMouse Anti-Rhesus HEXB Antibody is a mouse antibody against HEXB. It can be used for HEXB detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesBeta-hexosaminidase; EC 3.2.1.52; HEXB
UniProt IDI2CU07
Protein RefseqThe length of the protein is 556 amino acids long.
The sequence is show below: MELCGLGLPRPPMLLALLLATLLAAMLALLTQVALVVQVAEATRAPGVSAARGPALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHSYIFGFYKWDHEPAKSQATAQLQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVYQDSCGTFTINESTIIDSPRFPHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSIAFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMKQKGFGKDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKVKLAPGTIVEVWKDNAYPEELSKVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLDFGGTREQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDGAYDRLTRHRCRMVERGIAAQPLYAGYCNHENM.
For Research Use Only | Not For Clinical Use.
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