Mouse Anti-HEXB Antibody (CBMOAB-44499FYA)
Cat: CBMOAB-44499FYA
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
CBMOAB-44499FYA | Monoclonal | Rhesus (Macaca mulatta), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Marmoset, O. anatinus (Ornithorhynchus anatinus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries), Zebrafish (Danio rerio) | WB, ELISA | MO44499FYA | 100 µg | ||
CBMOAB-79383FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO79383FYA | 100 µg | ||
MO-AB-06551Y | Monoclonal | O. anatinus (Ornithorhynchus anatinus) | WB, ELISA | MO06551Y | 100 µg | ||
MO-AB-08019W | Monoclonal | Cat (Felis catus) | WB, ELISA | MO08019W | 100 µg | ||
MO-AB-08347Y | Monoclonal | Rabbit (Oryctolagus cuniculus) | WB, ELISA | MO08347Y | 100 µg | ||
MO-AB-13637R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO13637R | 100 µg | ||
MO-AB-15628Y | Monoclonal | Sheep (Ovis aries) | WB, ELISA | MO15628Y | 100 µg | ||
MO-AB-16236W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO16236W | 100 µg | ||
MO-AB-26312R | Monoclonal | Pig (Sus scrofa) | WB, ELISA | MO26312R | 100 µg | ||
MO-AB-31108W | Monoclonal | Dog (Canis lupus familiaris) | WB, ELISA | MO31108W | 100 µg | ||
MO-AB-34884W | Monoclonal | Ferret (Mustela Putorius Furo) | WB, ELISA | MO34884W | 100 µg | ||
MO-AB-56697W | Monoclonal | Marmoset | WB, ELISA | MO56697W | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Ferret (Mustela Putorius Furo), Marmoset, O. anatinus (Ornithorhynchus anatinus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries), Zebrafish (Danio rerio) |
Clone | MO44499FYA |
Specificity | This antibody binds to Rhesus HEXB. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Product Overview | Mouse Anti-Rhesus HEXB Antibody is a mouse antibody against HEXB. It can be used for HEXB detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Beta-hexosaminidase; EC 3.2.1.52; HEXB |
UniProt ID | I2CU07 |
Protein Refseq | The length of the protein is 556 amino acids long. The sequence is show below: MELCGLGLPRPPMLLALLLATLLAAMLALLTQVALVVQVAEATRAPGVSAARGPALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHSYIFGFYKWDHEPAKSQATAQLQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVYQDSCGTFTINESTIIDSPRFPHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSIAFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMKQKGFGKDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKVKLAPGTIVEVWKDNAYPEELSKVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLDFGGTREQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDGAYDRLTRHRCRMVERGIAAQPLYAGYCNHENM. |
For Research Use Only | Not For Clinical Use.
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