Anti-His1 Antibody (Cat MO-MMB-0686), Mouse IgG1
Cat: MO-MMB-0686
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MMB2 |
| Immunogen | The antibody was raised against a recombinant protein containing amino acids 109-256 of Drosophila melanogaster histone H1. This protein region is not conserved in mammals. This antibody is unlikely to cross-react with human, mouse, or rat histone H1. |
| Format | Liquid or Lyophilized |
| Buffer | PBS, 30% glycerol |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Protein A purified |
Application Information
| Application | ChIP, ChIP-Seq, IP, IF, WB |
| Application Notes | WB: 0.2-1 µg/mL The optimal dilution should be determined by the end user. |
Target
| Introduction | The nucleosome is the smallest subunit of chromatin and consists of 147 DNA base pairs wrapped around the core histone octamer (histone H2A, histone H2B, histone H3, and histone H4). Histone H1 is a linking histone protein that exists at the interface between the nucleosome core and the DNA entry/exit point. Histone H1 is responsible for building higher-order chromatin structures. Chromatin undergoes a variety of chemical modifications, including post-translational modifications of histones and methylation of cytosine residues in DNA. The reported histone modifications include acetylation, methylation, phosphorylation, ubiquitination, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, and play a major role in regulating gene expression. |
| Alternative Names | Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. |
| UniProt ID | P02255 |
See other products for " HIS1 "
| CBMOAB-01684CR | Mouse Anti-Yeast HIS1 Antibody (CBMOAB-01684CR) |
| MO-AB-00236W | Mouse Anti-Barrel medic His1 Antibody (MO-AB-00236W) |
| CBMOAB-04955HCB | Mouse Anti-C. elegans HIS1 Antibody (CBMOAB-04955HCB) |
| CBMOAB-20532FYA | Mouse Anti-D. melanogaster His1 Antibody (CBMOAB-20532FYA) |
For Research Use Only | Not For Clinical Use.
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