Mouse Anti-HLA-DMA Antibody (CBMOAB-44603FYA)
Cat: CBMOAB-44603FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product List
- Specifications
- Application Information
- Target
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Rabbit (Oryctolagus cuniculus) |
| Clone | MO44603FYA |
| Specificity | This antibody binds to Rhesus HLA-DMA. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma Membrane; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. |
| Product Overview | Mouse Anti-Rhesus HLA-DMA Antibody is a mouse antibody against HLA-DMA. It can be used for HLA-DMA detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | HLA class II histocompatibility antigen, DM alpha chain; HLA-DMA |
| UniProt ID | H9F465 |
| Protein Refseq | The length of the protein is 176 amino acids long. The sequence is show below: ADWAQEQGDAPAILFDKAFCEMMIQQIGPQLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGSGPTFVSAVDGLSFQAFSYLNITPEPSDIFSCIVTHEIDRYTAIAYWVPQNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFRKPCSGD. |
For Research Use Only | Not For Clinical Use.
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